Verwandte Artikel zu Multicomponent analysis using UV-visible spectrophotometer
Inhaltsangabe
In the present work, a simple, cost effective, reproducible and reliable method for simultaneous estimation of Glimepiride and Pioglitazone-HCl in bulk and marketed formulation using simultaneous equation was developed and validated. The developed method involved measurement of absorbances at wavelength of 228 nm and 265.5 nm ( absorption maxima of Glimepiride and Pioglitazone-HCl respectively), which these obeyed the principle of simultaneous equation method. Both the drugs obeyed Beer-Lambert's law in concentration ranges (For Glimepiride 4-20 and for Pioglitazone-HCl 10-50 mcg/ml). The validation parameters studied according to I.C.H Q2B guidelines.The recovery studies (found to be 100.3 % and 100.01 % respectively). The molar absorptivity and Sandell's sensitivity values show the sensitivity of the method. The values of coefficient of variance suggest high level of precision of the method.The LOD and LOQ value for Glimepiride were 0.0161 and 0.0486 mcg/ml and of Pioglitazone-HCl were 0.213 and 0.645g/ml respectively. The developed and validated method can successfully be applicable for the estimation of drug content in various marketed formulations.
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In the present work, a simple, cost effective, reproducible and reliable method for simultaneous estimation of Glimepiride and Pioglitazone-HCl in bulk and marketed formulation using simultaneous equation was developed and validated. The developed method involved measurement of absorbances at wavelength of 228 nm and 265.5 nm ( absorption maxima of Glimepiride and Pioglitazone-HCl respectively), which these obeyed the principle of simultaneous equation method. Both the drugs obeyed Beer-Lambert's law in concentration ranges (For Glimepiride 4-20 and for Pioglitazone-HCl 10-50 mcg/ml). The validation parameters studied according to I.C.H Q2B guidelines.The recovery studies (found to be 100.3 % and 100.01 % respectively). The molar absorptivity and Sandell's sensitivity values show the sensitivity of the method. The values of coefficient of variance suggest high level of precision of the method.The LOD and LOQ value for Glimepiride were 0.0161 and 0.0486 mcg/ml and of Pioglitazone-HCl were 0.213 and 0.645g/ml respectively. The developed and validated method can successfully be applicable for the estimation of drug content in various marketed formulations.
Biografía del autor
Dr. Suresh Jain(M.Pharm, PhD), Associate Professor in MMCP, MMU, Mullana(Ambala)-Haryana.He has 9.5 years of teaching and Industrial experience. About 20 M.Pharm Students has been awarded their degree under his supervision.He has 15 national and international publications in his credit. He is a life member of APTI,IPA and other professional bodies.
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Multicomponent analysis using UV-visible spectrophotometer
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VDM Verlag Dr. Mueller Aktiengesellschaft & Co. KG, 2014
ISBN 10: 3659563285
ISBN 13: 9783659563287
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Multicomponent analysis using UV-visible spectrophotometer
Verlag:
VDM Verlag Dr. Mueller Aktiengesellschaft & Co. KG, 2014
ISBN 10: 3659563285
ISBN 13: 9783659563287
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Multicomponent analysis using UV-visible spectrophotometer
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LAP LAMBERT Academic Publishing Jun 2014, 2014
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ISBN 13: 9783659563287
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In the present work, a simple, cost effective, reproducible and reliable method for simultaneous estimation of Glimepiride and Pioglitazone-HCl in bulk and marketed formulation using simultaneous equation was developed and validated. The developed method involved measurement of absorbances at wavelength of 228 nm and 265.5 nm ( absorption maxima of Glimepiride and Pioglitazone-HCl respectively), which these obeyed the principle of simultaneous equation method. Both the drugs obeyed Beer-Lambert s law in concentration ranges (For Glimepiride 4-20 and for Pioglitazone-HCl 10-50 mcg/ml). The validation parameters studied according to I.C.H Q2B guidelines.The recovery studies (found to be 100.3 % and 100.01 % respectively). The molar absorptivity and Sandell s sensitivity values show the sensitivity of the method. The values of coefficient of variance suggest high level of precision of the method.The LOD and LOQ value for Glimepiride were 0.0161 and 0.0486 mcg/ml and of Pioglitazone-HCl were 0.213 and 0.645 g/ml respectively. The developed and validated method can successfully be applicable for the estimation of drug content in various marketed formulations. 52 pp. Englisch. Bestandsnummer des Verkäufers 9783659563287
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Beispielbild für diese ISBN
Multicomponent analysis using UV-visible spectrophotometer
Verlag:
VDM Verlag Dr. Mueller Aktiengesellschaft & Co. KG, 2014
ISBN 10: 3659563285
ISBN 13: 9783659563287
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Anbieter: Biblios, Frankfurt am main, HESSE, Deutschland
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Multicomponent analysis using UV-visible spectrophotometer
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ISBN 10: 3659563285
ISBN 13: 9783659563287
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Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Jain SureshDr. Suresh Jain(M.Pharm, PhD), Associate Professor in MMCP, MMU, Mullana(Ambala)-Haryana.He has 9.5 years of teaching and Industrial experience. About 20 M.Pharm Students has been awarded their degree under his supervision. Bestandsnummer des Verkäufers 5164986
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Multicomponent analysis using UV-visible spectrophotometer
Verlag:
LAP LAMBERT Academic Publishing Jun 2014, 2014
ISBN 10: 3659563285
ISBN 13: 9783659563287
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Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland
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Taschenbuch. Zustand: Neu. Neuware -In the present work, a simple, cost effective, reproducible and reliable method for simultaneous estimation of Glimepiride and Pioglitazone-HCl in bulk and marketed formulation using simultaneous equation was developed and validated. The developed method involved measurement of absorbances at wavelength of 228 nm and 265.5 nm ( absorption maxima of Glimepiride and Pioglitazone-HCl respectively), which these obeyed the principle of simultaneous equation method. Both the drugs obeyed Beer-Lambert¿s law in concentration ranges (For Glimepiride 4-20 and for Pioglitazone-HCl 10-50 mcg/ml). The validation parameters studied according to I.C.H Q2B guidelines.The recovery studies (found to be 100.3 % and 100.01 % respectively). The molar absorptivity and Sandell¿s sensitivity values show the sensitivity of the method. The values of coefficient of variance suggest high level of precision of the method.The LOD and LOQ value for Glimepiride were 0.0161 and 0.0486 mcg/ml and of Pioglitazone-HCl were 0.213 and 0.645¿g/ml respectively. The developed and validated method can successfully be applicable for the estimation of drug content in various marketed formulations.Books on Demand GmbH, Überseering 33, 22297 Hamburg 52 pp. Englisch. Bestandsnummer des Verkäufers 9783659563287
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Multicomponent analysis using UV-visible spectrophotometer
Verlag:
LAP LAMBERT Academic Publishing, 2014
ISBN 10: 3659563285
ISBN 13: 9783659563287
Neu
Taschenbuch
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Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - In the present work, a simple, cost effective, reproducible and reliable method for simultaneous estimation of Glimepiride and Pioglitazone-HCl in bulk and marketed formulation using simultaneous equation was developed and validated. The developed method involved measurement of absorbances at wavelength of 228 nm and 265.5 nm ( absorption maxima of Glimepiride and Pioglitazone-HCl respectively), which these obeyed the principle of simultaneous equation method. Both the drugs obeyed Beer-Lambert s law in concentration ranges (For Glimepiride 4-20 and for Pioglitazone-HCl 10-50 mcg/ml). The validation parameters studied according to I.C.H Q2B guidelines.The recovery studies (found to be 100.3 % and 100.01 % respectively). The molar absorptivity and Sandell s sensitivity values show the sensitivity of the method. The values of coefficient of variance suggest high level of precision of the method.The LOD and LOQ value for Glimepiride were 0.0161 and 0.0486 mcg/ml and of Pioglitazone-HCl were 0.213 and 0.645 g/ml respectively. The developed and validated method can successfully be applicable for the estimation of drug content in various marketed formulations. Bestandsnummer des Verkäufers 9783659563287
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