Aconitum species are known to produce variously substituted diterpene alkaloids (DAs), many of which exhibit high toxicity and a broad spectrum of pharmacological effects. A research programme dealing with Aconitum species native to the Carpathian Basin has been started at the Department of Pharmacognosy, University of Szeged, in 2001. As a part of this still ongoing comprehensive phytochemical project, the alkaloid composition of Aconitum anthora and A. moldavicum was investigated. Besides the above the herein work reports the semisynthesis and purification of a series of lipo-alkaloids (LAs) derived from aconitine and the evaluation of the in vitro anti-inflammatory activity of these LAs, and the hERG and Nav1.2 channel activities of previously or newly isolated DAs; and the quantitative determination of toxic diester DAs in authentic processed A. carmichaelii and A. kusnezoffii samples. With the worldwide increasing spread of the Far Eastern traditional medicinal systems, and with the increasing public interest towards phytomedicines, pharmacological and phytoanalytical studies on aconite drugs are of growing importance and may be of interest for all who work in these fields.
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Aconitum species are known to produce variously substituted diterpene alkaloids (DAs), many of which exhibit high toxicity and a broad spectrum of pharmacological effects. A research programme dealing with Aconitum species native to the Carpathian Basin has been started at the Department of Pharmacognosy, University of Szeged, in 2001. As a part of this still ongoing comprehensive phytochemical project, the alkaloid composition of Aconitum anthora and A. moldavicum was investigated. Besides the above the herein work reports the semisynthesis and purification of a series of lipo-alkaloids (LAs) derived from aconitine and the evaluation of the in vitro anti-inflammatory activity of these LAs, and the hERG and Nav1.2 channel activities of previously or newly isolated DAs; and the quantitative determination of toxic diester DAs in authentic processed A. carmichaelii and A. kusnezoffii samples. With the worldwide increasing spread of the Far Eastern traditional medicinal systems, and with the increasing public interest towards phytomedicines, pharmacological and phytoanalytical studies on aconite drugs are of growing importance and may be of interest for all who work in these fields.
Botond Lajos BORCSA, Pharm. D., Ph.D.; Ph.D. studies: Graduate School of Pharmaceutical Sciences, University of Szeged; degree certificate of specialist pharmacist in pharmacognosy and phytotherapy, doctor of pharmacy (Pharm. D.) degree, English-Hungarian pharmaceutical translator and interpreter degree: Faculty of Pharmacy, University of Szeged
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Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Borcsa Botond LajosBotond Lajos BORCSA, Pharm. D., Ph.D. Ph.D. studies: Graduate School of Pharmaceutical Sciences, University of Szeged degree certificate of specialist pharmacist in pharmacognosy and phytotherapy, doctor of pharm. Bestandsnummer des Verkäufers 5169870
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Taschenbuch. Zustand: Neu. Neuware -Aconitum species are known to produce variously substituted diterpene alkaloids (DAs), many of which exhibit high toxicity and a broad spectrum of pharmacological effects. A research programme dealing with Aconitum species native to the Carpathian Basin has been started at the Department of Pharmacognosy, University of Szeged, in 2001. As a part of this still ongoing comprehensive phytochemical project, the alkaloid composition of Aconitum anthora and A. moldavicum was investigated. Besides the above the herein work reports the semisynthesis and purification of a series of lipo-alkaloids (LAs) derived from aconitine and the evaluation of the in vitro anti-inflammatory activity of these LAs, and the hERG and Nav1.2 channel activities of previously or newly isolated DAs; and the quantitative determination of toxic diester DAs in authentic processed A. carmichaelii and A. kusnezoffii samples. With the worldwide increasing spread of the Far Eastern traditional medicinal systems, and with the increasing public interest towards phytomedicines, pharmacological and phytoanalytical studies on aconite drugs are of growing importance and may be of interest for all who work in these fields.Books on Demand GmbH, Überseering 33, 22297 Hamburg 80 pp. Englisch. Bestandsnummer des Verkäufers 9783659633454
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Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Aconitum species are known to produce variously substituted diterpene alkaloids (DAs), many of which exhibit high toxicity and a broad spectrum of pharmacological effects. A research programme dealing with Aconitum species native to the Carpathian Basin has been started at the Department of Pharmacognosy, University of Szeged, in 2001. As a part of this still ongoing comprehensive phytochemical project, the alkaloid composition of Aconitum anthora and A. moldavicum was investigated. Besides the above the herein work reports the semisynthesis and purification of a series of lipo-alkaloids (LAs) derived from aconitine and the evaluation of the in vitro anti-inflammatory activity of these LAs, and the hERG and Nav1.2 channel activities of previously or newly isolated DAs; and the quantitative determination of toxic diester DAs in authentic processed A. carmichaelii and A. kusnezoffii samples. With the worldwide increasing spread of the Far Eastern traditional medicinal systems, and with the increasing public interest towards phytomedicines, pharmacological and phytoanalytical studies on aconite drugs are of growing importance and may be of interest for all who work in these fields. Bestandsnummer des Verkäufers 9783659633454
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Aconitum species are known to produce variously substituted diterpene alkaloids (DAs), many of which exhibit high toxicity and a broad spectrum of pharmacological effects. A research programme dealing with Aconitum species native to the Carpathian Basin has been started at the Department of Pharmacognosy, University of Szeged, in 2001. As a part of this still ongoing comprehensive phytochemical project, the alkaloid composition of Aconitum anthora and A. moldavicum was investigated. Besides the above the herein work reports the semisynthesis and purification of a series of lipo-alkaloids (LAs) derived from aconitine and the evaluation of the in vitro anti-inflammatory activity of these LAs, and the hERG and Nav1.2 channel activities of previously or newly isolated DAs; and the quantitative determination of toxic diester DAs in authentic processed A. carmichaelii and A. kusnezoffii samples. With the worldwide increasing spread of the Far Eastern traditional medicinal systems, and with the increasing public interest towards phytomedicines, pharmacological and phytoanalytical studies on aconite drugs are of growing importance and may be of interest for all who work in these fields. 80 pp. Englisch. Bestandsnummer des Verkäufers 9783659633454
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