Bioaccessibility of Cu and risk assessment models: Risk assessment and bioaccessibility - Softcover

Alsaleh, Khaled; Paton, Graeme

 
9783659674839: Bioaccessibility of Cu and risk assessment models: Risk assessment and bioaccessibility
Softcover
ISBN 10: 3659674834 ISBN 13: 9783659674839
Verlag: LAP LAMBERT Academic Publishing, 2015

Inhaltsangabe

The application of in vitro digestion assays as a surrogate for human ingestion studies is important when assessing potential risk of contaminants to humans. The assays simulate the release of contaminants from sample matrices (soil) in three-step procedure (mouth, stomach, small intestine). In this study, oral bioaccessibility of copper (Cu) was investigated using four laboratory spiked soils and one historically contaminated soil. Bioaccessibility correlated with the soil texture while soil pH has a lesser effect. Bioaccessibility in freshly amended soils was proportionally similar to that for historically contaminated soils; a finding that is different from that reported by other authors. Furthermore, assays using fasted scenarios yielded different results from fed assays. Measurements of metal assimilation through direct ingestion represent an important pathway for exposure and their relative empirical value enables an insight into the value of modelled data.

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Reseña del editor

The application of in vitro digestion assays as a surrogate for human ingestion studies is important when assessing potential risk of contaminants to humans. The assays simulate the release of contaminants from sample matrices (soil) in three-step procedure (mouth, stomach, small intestine). In this study, oral bioaccessibility of copper (Cu) was investigated using four laboratory spiked soils and one historically contaminated soil. Bioaccessibility correlated with the soil texture while soil pH has a lesser effect. Bioaccessibility in freshly amended soils was proportionally similar to that for historically contaminated soils; a finding that is different from that reported by other authors. Furthermore, assays using fasted scenarios yielded different results from fed assays. Measurements of metal assimilation through direct ingestion represent an important pathway for exposure and their relative empirical value enables an insight into the value of modelled data.

Biografía del autor

Dr. Khaled Alsaleh has obtained his PhD degree in Soil Science at King Saud University, Saudi Arabia, in 2014. His Master degree was in Environmental Science at Aberdeen University, Scotland/UK, in 2008. His bachelor's degree was in chemistry in 1998. He is interested in the field of environmental pollution and Quality Assurance.

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Verlag
LAP LAMBERT Academic Publishing
Erscheinungsdatum
2015
Sprache
Englisch
ISBN 10 
3659674834
ISBN 13 
9783659674839
Einband
Tapa blanda
Anzahl der Seiten
52
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