AKI- an underestimated problem in the pediatric intensive care - Softcover

Krastins Jekabs

Softcover

ISBN 10: 3659688509 ISBN 13: 9783659688508

Verlag: LAP Lambert Academic Publishing, 2015

Über diesen Titel

Reseña del editor:

Acute kidney injury (AKI) is increasingly recognized as a cause of increased morbidity in critically ill children and adults, and damage to the kidney, a central mediator of homeostasis in the body, affects patient survival. AKI is now known to be an independent risk factor for mortality,. The list of causes of AKI in pediatrics is long; however, the true etiology is likely multifactorial, related to a combination of several factors, such as ischemia and reperfusion injury, disruption of renal vasomotor homeostasis, hypoxic and oxidative stress, and cytokine-driven effects. The kidney is central to numerous homeostatic control mechanisms. Calculations of glomerular filtration rate (GFR) rely on serum creatinine (SCr) and are often unreliable because of variability within age groups, gender, metabolic state, body composition, and excretion by the kidney itself. Definitions of oliguria, also are varied. This book is focused on evidence-based AKI research, highlighting disturbing epidemiologic trends for pediatric AKI, novel detection strategies, the role of AKI as an independent causative agent of injury, and available evidence-based data regarding management and outcomes.

Über diese Auflage

• Verlag: LAP Lambert Academic Publishing
• Erscheinungsdatum: 2015
• ISBN 10: 3659688509
• ISBN 13: 9783659688508
• Einband: Tapa blanda
• Anzahl der Seiten: 84