Periodontal diseases are initiated by Gram-negative tooth associated microbial biofilms that elicit a host response, with resultant osseous and soft tissue destruction. In response to endotoxins derived from periodontal pathogens, several osteoclast- related mediators target the destruction of alveolar bone and supporting connective tissues. Major drivers of this aggressive tissue destruction are matrix metalloproteinases (MMPs), cathepsins,cytokines and other osteoclast-derived enzymes. This book focuses on the downstream factors of the osteoclast responsible for the degradation of bone and soft tissues around teeth. Furthermore various therapeutic approaches that target MMPs, cytokines,cathepsins and other osteoclast-derived enzymes , such as MMP inhibitors, chemically modified tetracyclines, subantimicrobial formulations of tetracycline analogues, and various new agents such as periodontal vaccines, Probiotics, Grape seed proanthocyanidins, Cranberry fraction, omega 3 fatty acid, locally administered HMT agents are discussed. In addition, studies using other agents for the preservation of bone mass, such as bisphosphonates that inhibit osteoclast recruitment, are highlighted.
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Il dottor Amol Beldar è lettore e guida post-laurea presso il Dipartimento di Parodontologia e Implantologia del MGV's KBH Dental College and Hospital. Ha al suo attivo molti articoli scientifici nazionali e internazionali. La dottoressa Priya Vijay Thakkar e la dottoressa Merekhna Raghavan sono studentesse post-laurea nel dipartimento di parodontologia e implantologia presso il MGV's KBH Dental College.
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Periodontal diseases are initiated by Gram-negative tooth associated microbial biofilms that elicit a host response, with resultant osseous and soft tissue destruction. In response to endotoxins derived from periodontal pathogens, several osteoclast- related mediators target the destruction of alveolar bone and supporting connective tissues. Major drivers of this aggressive tissue destruction are matrix metalloproteinases (MMPs), cathepsins,cytokines and other osteoclast-derived enzymes. This book focuses on the downstream factors of the osteoclast responsible for the degradation of bone and soft tissues around teeth. Furthermore various therapeutic approaches that target MMPs, cytokines,cathepsins and other osteoclast-derived enzymes , such as MMP inhibitors, chemically modified tetracyclines, subantimicrobial formulations of tetracycline analogues, and various new agents such as periodontal vaccines, Probiotics, Grape seed proanthocyanidins, Cranberry fraction, omega 3 fatty acid, locally administered HMT agents are discussed. In addition, studies using other agents for the preservation of bone mass, such as bisphosphonates that inhibit osteoclast recruitment, are highlighted. 84 pp. Englisch. Bestandsnummer des Verkäufers 9783659922954
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Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Periodontal diseases are initiated by Gram-negative tooth associated microbial biofilms that elicit a host response, with resultant osseous and soft tissue destruction. In response to endotoxins derived from periodontal pathogens, several osteoclast- related mediators target the destruction of alveolar bone and supporting connective tissues. Major drivers of this aggressive tissue destruction are matrix metalloproteinases (MMPs), cathepsins,cytokines and other osteoclast-derived enzymes. This book focuses on the downstream factors of the osteoclast responsible for the degradation of bone and soft tissues around teeth. Furthermore various therapeutic approaches that target MMPs, cytokines,cathepsins and other osteoclast-derived enzymes , such as MMP inhibitors, chemically modified tetracyclines, subantimicrobial formulations of tetracycline analogues, and various new agents such as periodontal vaccines, Probiotics, Grape seed proanthocyanidins, Cranberry fraction, omega 3 fatty acid, locally administered HMT agents are discussed. In addition, studies using other agents for the preservation of bone mass, such as bisphosphonates that inhibit osteoclast recruitment, are highlighted.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 84 pp. Englisch. Bestandsnummer des Verkäufers 9783659922954
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Taschenbuch. Zustand: Neu. Recent concepts in host modulation therapy | Priya Vijay Thakkar (u. a.) | Taschenbuch | 84 S. | Englisch | 2016 | LAP LAMBERT Academic Publishing | EAN 9783659922954 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. Bestandsnummer des Verkäufers 102880253
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