Assessment of the Use of Single Cytochrome P450 Enzymes in Drug Research: 13 (Ernst Schering Foundation Symposium Proceedings) - Softcover

 
9783662030219: Assessment of the Use of Single Cytochrome P450 Enzymes in Drug Research: 13 (Ernst Schering Foundation Symposium Proceedings)
Softcover
ISBN 10: 3662030217 ISBN 13: 9783662030219
Verlag: Springer, 2012

Inhaltsangabe

Metabolic research and especially that which focuses on the monooxygenase cytochrome P450 system has gone through dramatic progressive changes within the last decade. Availability of highly sophisticated analytical techniques has contributed to increased molecular understanding of biotransformation pathways. Nowadays designer drugs are computer composable focussing on metabolic stability. The rapid development of recombinant enzymes has, in many cases, replaced the intensive work on P450 isolation from naturally occurring sources. Recombinant P450s can be expressed in cell lines and thus made available for reproducible and constant use addressig a large number of scientific questions. This book describes the present position of such research.

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Reseña del editor

Metabolic research and especially that which focuses on the monooxygenase cytochrome P450 system has gone through dramatic progressive changes within the last decade. Availability of highly sophisticated analytical techniques has contributed to increased molecular understanding of biotransformation pathways. Nowadays designer drugs are computer composable focussing on metabolic stability. The rapid development of recombinant enzymes has, in many cases, replaced the intensive work on P450 isolation from naturally occurring sources. Recombinant P450s can be expressed in cell lines and thus made available for reproducible and constant use addressig a large number of scientific questions. This book describes the present position of such research.

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Verlag
Springer
Erscheinungsdatum
2012
Sprache
Englisch
ISBN 10 
3662030217
ISBN 13 
9783662030219
Einband
Tapa blanda
Anzahl der Seiten
240
Herausgeber
Waterman M.R., Hildebrand M.
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9783540583431: Assessment of the Use of Single Cytochrome P450 Enzymes in Drug Research: v. 13 (Ernst Schering Foundation Symposium Proceedings)

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