Verwandte Artikel zu Leucocyte Trafficking: The Role of Fucosyltransferases...

Leucocyte Trafficking: The Role of Fucosyltransferases and Selectins - Softcover

A. Hamann

 
9783662053980: Leucocyte Trafficking: The Role of Fucosyltransferases and Selectins

Inhaltsangabe

An essential component of inflammation is the migration of circulating leukocytes from blood into tissues. This process is characterized by a multistep paradigm of sequential cell adhesion and activation events that lead to the extravasation of specific leukocyte subsets to different tissues in health and disease. The first step of leukocyte extravasation, the rolling of leukocytes, is primarily mediated by the interactions of selectins and their ligands. It has recently become evident that fucosyltransferases are crucial for selectin ligand synthesis, inflammation, and skin homing. This book provides an in-depth overview of the mechanisms of leukocyte trafficking and of the molecular mechanisms of selectin/selectin ligand interactions and discusses options for pharmacological intervention to treat inflammatory diseases.

Die Inhaltsangabe kann sich auf eine andere Ausgabe dieses Titels beziehen.

Weitere beliebte Ausgaben desselben Titels

9783540401124: Leucocyte Trafficking: The Role of Fucosyltransferases and Selectins (Ernst Schering Foundation Symposium Proceedings, 44, Band 44)

Vorgestellte Ausgabe

ISBN 10:  3540401121 ISBN 13:  9783540401124
Verlag: Springer, 2003
Hardcover