Homocysteine in Protein Structure/Function and Human Disease: Chemical Biology of Homocysteine-containing Proteins - Hardcover

Jakubowski, Hieronim

 
9783709114094: Homocysteine in Protein Structure/Function and Human Disease: Chemical Biology of Homocysteine-containing Proteins
Hardcover
ISBN 10: 3709114098 ISBN 13: 9783709114094
Verlag: Springer, 2013

Inhaltsangabe

Excess of homocysteine, a product of the metabolism of the essential amino acid methionine, is associated with poor health, is linked to heart and brain diseases in general human populations, and accelerates mortality in heart disease patients. Neurological and cardiovascular abnormalities occur in patients with severe genetic hyperhomocysteinemia and lead to premature death due to vascular complications. Although it is considered a non-protein amino acid, studies over the past dozen years have discovered mechanisms by which homocysteine becomes a component of proteins. Homocysteine-containing proteins lose their normal biological function and become auto-immunogenic and pro-thrombotic. In this book, the author, a pioneer and a leading contributor to the field, describes up-to date studies of the biological chemistry of homocysteine-containing proteins, as well as pathological consequences and clinical implications of their formation. This is a comprehensive account of the broad rangeof basic science and medical implications of homocysteine-containing proteins for health and disease. ​

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Von der hinteren Coverseite

Excess of homocysteine, a product of the metabolism of the essential amino acid methionine, is associated with poor health, is linked to heart and brain diseases in general human populations, and accelerates mortality in heart disease patients. Neurological and cardiovascular abnormalities occur in patients with severe genetic hyperhomocysteinemia and lead to premature death due to vascular complications. Although it is considered a non-protein amino acid, studies over the past dozen years have discovered mechanisms by which homocysteine becomes a component of proteins. Homocysteine-containing proteins lose their normal biological function and become auto-immunogenic and pro-thrombotic. In this book, the author, a pioneer and a leading contributor to the field, describes up-to date studies of the biological chemistry of homocysteine-containing proteins, as well as pathological consequences and clinical implications of their formation. This is a comprehensive account of the broad rangeof basic science and medical implications of homocysteine-containing proteins for health and disease. ​

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Verlag
Springer
Erscheinungsdatum
2013
Sprache
Englisch
ISBN 10 
3709114098
ISBN 13 
9783709114094
Einband
Gebundene Ausgabe
Anzahl der Seiten
179
Kontakt zum Hersteller
ProductSafety@springernature.com
ProductSafety@springernature.com

Poststr. 9
Darmstadt
64293
Deutschland

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Vorgestellte Ausgabe

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Softcover