Natural Compounds as Drugs, Volume I: 65 (Progress in Drug Research) - Hardcover

Hardcover

ISBN 10: 3764380985 ISBN 13: 9783764380984

Verlag: Springer, 2007

Inhaltsangabe

The use of herbal medicines, their preparation and application in human therapy, was described for the first time in history by the Sumerians approximately 5000 years ago. Even earlier in India and China, a highly sophisticated medical system with plant-based therapies had been dev- oped. Along with the rise of the later empires, this knowledge was further expanded and institutionalized, while moving westwards to Egypt, Greece, and to the Arabic world, having a considerable influence on human th- apy – until today. Not all of these traditional medicines, although partially in medical practice still today, can be considered as efficacious or useful according to Western therapeutic standards, often due to the fact that the tra- tional disease categories cannot be easily translated into the “language” of Western medicine. The identification of active principles from plant preparations often failed, as the biological activity could not be enriched. However, there are numerous examples like morphine, quinine, salicylic acid, rivastigmine, digitalis glycosides, reserpine, or artemisinine, where the correlation between plant extract and the modern medicine, based on a single entity drug, was successfully established. All of these natural pr- ucts originated from traditional medical practice and opened the door to today’s medical indication areas, fundamentally enriching our knowledge of the pathophysiology and underlying biochemistry of diseases.

Über diesen Titel

Von der hinteren Coverseite

The use of drug substances derived from plants, fungi, bacteria, and marine organisms has a long tradition in medicine. Together with their derivatives, and synthetic compounds deduced from natural product precursors, they represent a major part of today's pharmaceutical market.

Within the fast developing discipline of molecular biology, natural products also play an important role as tool compounds in pathway screening and validation of target identification concepts. They provide innovative opportunities in drug discovery, leading to a detailed understanding of biological pathways and revealing the functions of involved enzymes or receptors.

This book highlights new trends and aspects in natural products research. It discusses the biodiversity-driven approaches which are now of eminent importance in natural products research, addressing the question why natural products display such a complex chemical information, what makes them often unique and what their characteristics are. Practical questions such as supply of natural substances and production optimization strategies are also covered.

Details zur Ausgabe

• Verlag: Springer
• Erscheinungsdatum: 2007
• Sprache: Englisch
• ISBN 10: 3764380985
• ISBN 13: 9783764380984
• Einband: Tapa dura
• Anzahl der Seiten: 384
• Herausgeber: Petersen Frank, Amstutz René
• Kontakt zum Hersteller: Nicht verfügbar
• Verantwortliche Person: Nicht verfügbar