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Th 17 Cells: Role in Inflammation and Autoimmune Disease (Progress in Inflammation Research) - Hardcover

 
9783764386801: Th 17 Cells: Role in Inflammation and Autoimmune Disease (Progress in Inflammation Research)
Hardcover
ISBN 10: 3764386800 ISBN 13: 9783764386801
Verlag: Birkhäuser, 2008

Inhaltsangabe

With the recent definition of the Th17 cell subset, a new paradigm in innate and adaptive immunity has been established. This book describes the function of the Th17 cell subset and its prevalent role in many inflammatory and autoimmune diseases. The mechanism by which this T cell subset is generated and maintained shows specific differences between mice and man which are reviewed. One characteristic of Th17 cells is to secrete specific and unique cytokines such as IL-17A, IL-17F and IL-22; their functions are described in detail. These cytokines have acquired a prevalent role in many pathological conditions in animal models and in humans. Targeting these cytokines as well as the generation of Th17 cells may open new ways to treat many autoimmune diseases. The role of Th17 in infectious conditions is also addressed.

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With the recent definition of the Th17 cell subset, a new paradigm in innate and adaptive immunity has been established. This book describes the function of the Th17 cell subset and its prevalent role in many inflammatory and autoimmune diseases. The mechanism by which this T cell subset is generated and maintained shows specific differences between mice and man which are reviewed. One characteristic of Th17 cells is to secrete specific and unique cytokines such as IL-17A, IL-17F and IL-22; their functions are described in detail. These cytokines have acquired a prevalent role in many pathological conditions in animal models and in humans. Targeting these cytokines as well as the generation of Th17 cells may open new ways to treat many autoimmune diseases. The role of Th17 in infectious conditions is also addressed.

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Verlag
Birkhäuser
Erscheinungsdatum
2008
Sprache
Englisch
ISBN 10 
3764386800
ISBN 13 
9783764386801
Einband
Gebundene Ausgabe
Anzahl der Seiten
256
Herausgeber
Quesniaux Valérie, Ryffel Bernhard, Padova Franco
Kontakt zum Hersteller
Springer Heidelberg
buchhandel-buch@springer.com

Tiergartenstr. 17
Heidelberg
69121
Deutschland