Application of the Difference Map Algorithm to Protein Structure Prediction - Softcover

Rankenburg, Ivan

Softcover

ISBN 10: 383647106X ISBN 13: 9783836471060

Verlag: VDM Verlag Dr. Mueller E.K., 2008

Inhaltsangabe

A powerful new search algorithm, the difference map, has had notable success in many fields that involve finding a characteristic point in a high dimensional search space. The algorithm was first applied to a toy model of proteins in 2004. In that context, the difference map was able to find low energy "folds" better than any contemporary search algorithm. In this work, the same algorithm is applied to a realistic protein model. Though the algorithm finds low energy folds for the protein molecule, the energy function used is found to be inadequate to make the lowest energy state of the protein molecule the native conformation. In this work, the algorithm is described, and some example applications are given. Finally, the complete programming implementation of the algorithm to the problem of protein energy minimization is supplied.

Details zur Ausgabe

• Verlag: VDM Verlag Dr. Mueller E.K.
• Erscheinungsdatum: 2008
• Sprache: Englisch
• ISBN 10: 383647106X
• ISBN 13: 9783836471060
• Einband: Taschenbuch
• Anzahl der Seiten: 184
• Kontakt zum Hersteller: Nicht verfügbar
• Verantwortliche Person: preigu; mail@preigu.de; ; Lengericher Landstr. 19; Osnabrück; 49078; Deutschland