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R-Ras Proteins, TGF-Beta and Cancer: Mechanisms of Interaction Among the R-Ras, TC21 and TGF-Beta Signaling Pathways - Softcover

Erdogan, Mete

 
9783838306643: R-Ras Proteins, TGF-Beta and Cancer: Mechanisms of Interaction Among the R-Ras, TC21 and TGF-Beta Signaling Pathways
Softcover
ISBN 10: 3838306643 ISBN 13: 9783838306643
Verlag: LAP Lambert Academic Publishing, 2009

Inhaltsangabe

During the progression of human cancers, normal cells acquire genetic and epigenetic changes in the signaling pathways that govern their proliferation, resulting in uncontrolled growth and tumor formation. Oncogenic Ras and Transforming Growth Factor-Beta are known to cooperate in promoting malignant transformation, yet the mechanism by which they interact has not been established. Here, we present novel mechanisms through which Transforming Growth Factor-Beta interacts with two Ras-related proteins, R-Ras and TC21, to transform mammary epithelial cells.

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Über die Autorin bzw. den Autor

Mete Erdogan obtained a PhD in Cancer Biology from Vanderbilt University in Nashville, TN (USA). Presently, he is pursuing a Postdoctoral Fellowship in Cancer Biology at Dalhousie University in Halifax, Canada.

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Verlag
LAP Lambert Academic Publishing
Erscheinungsdatum
2009
Sprache
Englisch
ISBN 10 
3838306643
ISBN 13 
9783838306643
Einband
Taschenbuch
Anzahl der Seiten
112
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
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