Development And Evaluation of Carvedilol SR Tablet: Formulation Development - Softcover

Halder, Shimul; Shuma, Madhabi Lata; Rouf, Abu Shara Shamsur

 
9783846511251: Development And Evaluation of Carvedilol SR Tablet: Formulation Development
Softcover
ISBN 10: 3846511250 ISBN 13: 9783846511251
Verlag: LAP LAMBERT Academic Publishing, 2011

Inhaltsangabe

Matrix tablets containing carvedilol phosphate were prepared using 27 formulations in three batch series where different ratios of K4M CR and K15M CR were used as release retarding agents. Avicel PH 101, Starch 1500 and Lactose monohydrate were used as diluents in the formulation of three batches. The data were subjected to different models in order to evaluate their release kinetics and mechanisms. Tablets in case of all formulations showed more than 50% of drug release in 12 h when Methocel K4M CR and K15M CR constituted 18% and 15% of the matrix respectively. It was found that Avicel PH 101 decreases while Starch 1500 and Lactose monohydrate increases drug release.

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Über die Autorin bzw. den Autor

Shimul Halder,M. Pharm, lecturer, Department of Pharmaceutical Technology,Faculty of Pharmacy,University of Dhaka,Bangladesh.

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Verlag
LAP LAMBERT Academic Publishing
Erscheinungsdatum
2011
Sprache
Englisch
ISBN 10 
3846511250
ISBN 13 
9783846511251
Einband
Taschenbuch
Anzahl der Seiten
144
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Verantwortliche Person
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