Inhaltsangabe
Impurity profiling and drug degradation pathways are essentials features for regulatory acceptance of any new drug entity. Despite of technological advancements in pharmaceutical analysis, structural elucidation of drug molecules, impurities produced during formulation remains challenging tasks for researchers. Unique chemical behavior, complex properties and interactions of different functional groups involved in active pharmaceutical ingredients along with different chemical environments with excipients and storage condition further complicate the issues. Furthermore isolation and characterization of impurities with special references to toxic metabolites is essential for acceptance of new drug molecules by regulatory agencies. Recently discovered and patented nitrate esters of paracetamol having improved analgesic and anti-inflammatory activities then parent drug and less hepatotoxicity in overdose is selected as model drug entity. This book is an attempt to provide experimental insights into the chemical, analytical and establishment of drug degradation pathways in forced conditions in lucid manner for easy understanding to meet future expectations of scientific fraternities.
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Über die Autorin bzw. den Autor
Dr. Neeraj Mishra is currently working as associate professor in ISF College of Pharmacy, Moga, Punjab, India. With 1 patent and over 40 publications of International and National repute, he is an active researcher in Pharmaceutical Sciences. He has supervised 20 M Pharm and B Pharm students.He was also awarded by ICMR- SRF for his Ph.D. work
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Impurity Profiling of a New Drug Entity
Verlag:
LAP LAMBERT Academic Publishing Feb 2014, 2014
ISBN 10: 3846580120
ISBN 13: 9783846580127
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Impurity profiling and drug degradation pathways are essentials features for regulatory acceptance of any new drug entity. Despite of technological advancements in pharmaceutical analysis, structural elucidation of drug molecules, impurities produced during formulation remains challenging tasks for researchers. Unique chemical behavior, complex properties and interactions of different functional groups involved in active pharmaceutical ingredients along with different chemical environments with excipients and storage condition further complicate the issues. Furthermore isolation and characterization of impurities with special references to toxic metabolites is essential for acceptance of new drug molecules by regulatory agencies. Recently discovered and patented nitrate esters of paracetamol having improved analgesic and anti-inflammatory activities then parent drug and less hepatotoxicity in overdose is selected as model drug entity. This book is an attempt to provide experimental insights into the chemical, analytical and establishment of drug degradation pathways in forced conditions in lucid manner for easy understanding to meet future expectations of scientific fraternities. 80 pp. Englisch. Bestandsnummer des Verkäufers 9783846580127
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Impurity Profiling of a New Drug Entity
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Impurity Profiling of a New Drug Entity
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Impurity Profiling of a New Drug Entity
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VDM Verlag Dr. Mueller Aktiengesellschaft & Co. KG, 2014
ISBN 10: 3846580120
ISBN 13: 9783846580127
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Impurity Profiling of a New Drug Entity
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Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Mishra NeerajDr. Neeraj Mishra is currently working as associate professor in ISF College of Pharmacy, Moga, Punjab, India. With 1 patent and over 40 publications of International and National repute, he is an active researcher in Ph. Bestandsnummer des Verkäufers 5501019
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Impurity Profiling of a New Drug Entity
Verlag:
LAP LAMBERT Academic Publishing Feb 2014, 2014
ISBN 10: 3846580120
ISBN 13: 9783846580127
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Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Impurity profiling and drug degradation pathways are essentials features for regulatory acceptance of any new drug entity. Despite of technological advancements in pharmaceutical analysis, structural elucidation of drug molecules, impurities produced during formulation remains challenging tasks for researchers. Unique chemical behavior, complex properties and interactions of different functional groups involved in active pharmaceutical ingredients along with different chemical environments with excipients and storage condition further complicate the issues. Furthermore isolation and characterization of impurities with special references to toxic metabolites is essential for acceptance of new drug molecules by regulatory agencies. Recently discovered and patented nitrate esters of paracetamol having improved analgesic and anti-inflammatory activities then parent drug and less hepatotoxicity in overdose is selected as model drug entity. This book is an attempt to provide experimental insights into the chemical, analytical and establishment of drug degradation pathways in forced conditions in lucid manner for easy understanding to meet future expectations of scientific fraternities.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 80 pp. Englisch. Bestandsnummer des Verkäufers 9783846580127
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Impurity Profiling of a New Drug Entity : Experimental Insights
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LAP LAMBERT Academic Publishing, 2014
ISBN 10: 3846580120
ISBN 13: 9783846580127
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Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Impurity profiling and drug degradation pathways are essentials features for regulatory acceptance of any new drug entity. Despite of technological advancements in pharmaceutical analysis, structural elucidation of drug molecules, impurities produced during formulation remains challenging tasks for researchers. Unique chemical behavior, complex properties and interactions of different functional groups involved in active pharmaceutical ingredients along with different chemical environments with excipients and storage condition further complicate the issues. Furthermore isolation and characterization of impurities with special references to toxic metabolites is essential for acceptance of new drug molecules by regulatory agencies. Recently discovered and patented nitrate esters of paracetamol having improved analgesic and anti-inflammatory activities then parent drug and less hepatotoxicity in overdose is selected as model drug entity. This book is an attempt to provide experimental insights into the chemical, analytical and establishment of drug degradation pathways in forced conditions in lucid manner for easy understanding to meet future expectations of scientific fraternities. Bestandsnummer des Verkäufers 9783846580127
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Impurity Profiling of a New Drug Entity | Experimental Insights
Verlag:
LAP LAMBERT Academic Publishing, 2014
ISBN 10: 3846580120
ISBN 13: 9783846580127
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Taschenbuch. Zustand: Neu. Impurity Profiling of a New Drug Entity | Experimental Insights | Neeraj Mishra (u. a.) | Taschenbuch | 80 S. | Englisch | 2014 | LAP LAMBERT Academic Publishing | EAN 9783846580127 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. Bestandsnummer des Verkäufers 105425828
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