Bioinformatic Approaches to Structure and Function of Protein: Structural and Functional Analysis of Rhodopsin - Softcover

Kanwal, Shagufta; NIshat, Sumaira; Khan, Muhammad Irfan

 
9783846584361: Bioinformatic Approaches to Structure and Function of Protein: Structural and Functional Analysis of Rhodopsin
Softcover
ISBN 10: 3846584363 ISBN 13: 9783846584361
Verlag: LAP LAMBERT Academic Publishing, 2012

Inhaltsangabe

This book provides a compact knowledge about practical applications of bioinformatic approaches to understand the structure and function of a protein- Rhodesian which is found in visual pigment of eye and responsible for controlling night vision. Its structure has been predicted by comparative homology modelling and model evaluation through various tools. The electron density maps of retinal isomers and structure of rhodopsin intermediates were analyzed by structure superimposition. On the basis of structural analysis of thirteen mutations for Autosomal Dominant Retinitis Pigmentosa, one of the missense mutation has been targeted to propose a drug to cure night blindness. The molecular docking technique has also been used to predict ligand interactions with rhodopsin. It is hoped that this will provide new insights into structural and functional exploration of proteins which will be helpful in understanding various vital phenomena like protein activation and inhibition, drug interactions and protein signaling.

Die Inhaltsangabe kann sich auf eine andere Ausgabe dieses Titels beziehen.

Verlag
LAP LAMBERT Academic Publishing
Erscheinungsdatum
2012
Sprache
Englisch
ISBN 10 
3846584363
ISBN 13 
9783846584361
Einband
Taschenbuch
Anzahl der Seiten
128
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
Fastbook Publishing
customerservice@vdm-vsg.de

Brivibas gatve 197
Riga
1039
Lettland