Process Optimization of Diclofenac Sodium Sustained Release Tablet: Dosage Form Development - Softcover

Patel, Balkrushna K.; Raval, Bhuvan P.; Patel, Bhavik A.

 
9783847302834: Process Optimization of Diclofenac Sodium Sustained Release Tablet: Dosage Form Development
Softcover
ISBN 10: 3847302833 ISBN 13: 9783847302834
Verlag: LAP LAMBERT Academic Publishing, 2011

Inhaltsangabe

In this work an attempt has been done to optimize the process of tabletting and enteric coating for Diclofenac sodium enteric coated tablet. Various optimized parameters are Blending, Granulation, Compression, and Coating. All materials required for preparing Diclofenac 50mg enteric coated tablet were accurately dispensed under specified condition. Optimization was done based on determining the relationship between independent variable and dependent variable. Independent variable like blending time before granulation was optimized based on content uniformity. Spray rate of binder for granulation was optimized for uniform and satisfied physical characterization. Spray rate of enteric coating suspension was optimized for efficient coating and process.

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Über die Autorin bzw. den Autor

Balkrushna K. Patel, M. Pharm, (Ph.D.) is an Asst. Professor at K J College of Pharmacy. He has two international publications to his credit. Bhuvan P. Raval, M. Pharm, PGDPRA, MBA, (Ph.D), FSAB is an Asst. Professor at K J College of Pharmacy. Bhavik A. Patel, M. Pharm, (Ph.D.) is an Asst. Professor at K J College of Pharmacy.

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Verlag
LAP LAMBERT Academic Publishing
Erscheinungsdatum
2011
Sprache
Englisch
ISBN 10 
3847302833
ISBN 13 
9783847302834
Einband
Tapa blanda
Anzahl der Seiten
92
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