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Studies in Development of Fluid Bed Granulation Technology: Optimization & Development - Softcover

Patel, Tejas B; Bharadia, P. D; Patel, L.D

 
9783847328001: Studies in Development of Fluid Bed Granulation Technology: Optimization & Development
Softcover
ISBN 10: 384732800X ISBN 13: 9783847328001
Verlag: LAP LAMBERT Academic Publishing, 2011

Inhaltsangabe

The fluid bed granulation is a fairly complex process that can be divided in three steps: (1) Wetting and nucleation, (2) consolidation and growth and (3) breakage and attrition. Process parameters and physicochemical properties of the binder and granule substrate can have significant impact on these rate process and consequently the physical properties of the granule formed. The fluid bed granulation process is a influenced by various processing parameters like atomization pressure, binder addition rate, in let temperature, binder concentration etc. These process variables largely affect the granulation efficiency and the final granule characteristics so one should consider the process variable effect on granulation mechanism while developing a fluid bed granulation process for the any kind of the material that is to be granulated via this process. Granules prepared by this technology generally have good flow property but % porosity of the granules is higher then the granules prepared by the other convention granulation technique, has a good compressibility; and good flowability.

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Über die Autorin bzw. den Autor

Tejas B Patel, studied M. Pharm in pharmaceutics and pharmceutical technology at Shree S.K. Patel college of pharmaceutical education and research, Ganpat Vidyanagar, AT and PO: Kherava, dist: Mehsana, state: Gujrat, India. Currently working as Assistant Professor at Faculty of Pharmacy, Dharmsinh Desai University, Nadiad, Gujarat, India.

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Verlag
LAP LAMBERT Academic Publishing
Erscheinungsdatum
2011
Sprache
Englisch
ISBN 10 
384732800X
ISBN 13 
9783847328001
Einband
Taschenbuch
Anzahl der Seiten
116
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
GPSR Kontakt
info@bod.de

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