Multiple Alignments, Hidden Markov Models and SVMs: Development of a Computational Framework for Protein Homology Detection by Incorporating Realignment Algorithm - Softcover

Abdullah, Mohamad Firdaus; Othman, Razib M

Softcover

ISBN 10: 384733171X ISBN 13: 9783847331711

Verlag: LAP LAMBERT Academic Publishing, 2012

Inhaltsangabe

Remote protein homology detection is a problem of detecting evolutionary relationship between proteins at low sequence similarity level. Among several problems in remote protein homology detection include the questions of determining which combination of multiple alignment and classification techniques is the best as well as the misalignment of protein sequences during the alignment process. Therefore, this study deals with remote protein homology detection via assessing the impact of using structural information on protein multiple alignments over sequence information. This study further presents the best combinations of multiple alignment and classification programs to be chosen. This study also improves the quality of the multiple alignments via integration of a refinement algorithm.

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Über die Autorin bzw. den Autor

Mohamad Firdaus Abdullah has obtained his Masters Degree in Computer Science in 2010. Since then he has joined the industry and worked as internal software developer for a local based company in Malaysia.Dr. Razib M. Othman has obtained his PhD in Computer Science in 2008. Since then he has published numerous journal papers and book chapters.

Details zur Ausgabe

• Verlag: LAP LAMBERT Academic Publishing
• Erscheinungsdatum: 2012
• Sprache: Englisch
• ISBN 10: 384733171X
• ISBN 13: 9783847331711
• Einband: Taschenbuch
• Anzahl der Seiten: 164
• Kontakt zum Hersteller: Nicht verfügbar
• Verantwortliche Person: Editions Muse; customerservice@vdm-vsg.de; ; Brivibas gatve 197; Riga; 1039; Lettland