Computational Pipeline for Human Transcriptome quantification: Computational Pipeline for Human Transcriptome Quantification using RNA-seq data - Softcover

Xu, Guorong

Softcover

ISBN 10: 3847340530 ISBN 13: 9783847340539

Verlag: LAP LAMBERT Academic Publishing, 2012

Inhaltsangabe

The main theme of this thesis research is concerned with developing a computational pipeline for processing Next-generation RNA sequencing (RNA-seq) data. RNA-seq experiments generate tens of millions of short reads for each DNA/RNA sample. The alignment of a large volume of short reads to a reference genome is a key step in NGS data analysis. Although storing alignment information in the Sequence Alignment/Map (SAM) or Binary SAM (BAM) format is now standard, biomedical researchers still have difficulty accessing useful information. In order to assist biomedical researchers to conveniently access essential information from NGS data files in SAM/BAM format, we have developed a Graphical User Interface (GUI) software tool named SAMMate to pipeline human transcriptome quantification. SAMMate allows researchers to easily process NGS data files in SAM/BAM format and is compatible with both single-end and paired-end sequencing technologies. It also allows researchers to accurately calculate gene expression abundance scores.

Über diesen Titel

Über die Autorin bzw. den Autor

Guorong Xu was born in Hunan province, China on October 3rd 1977. He received his master degree in the department of Computer Science in 2011. And then he continue his further study in Bioinformatics area.

Details zur Ausgabe

• Verlag: LAP LAMBERT Academic Publishing
• Erscheinungsdatum: 2012
• Sprache: Englisch
• ISBN 10: 3847340530
• ISBN 13: 9783847340539
• Einband: Taschenbuch
• Anzahl der Seiten: 84
• Kontakt zum Hersteller: Nicht verfügbar
• Verantwortliche Person: KreGa Onlinehandel GmbH; 4950000000000; info@krega-onlinehandel.de; ; Birkenweg 31; Brakel; 33034; Deutschland