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Insilico study of Type II Diabetes and Effective drugs: A Bioinformatics study of Diabetes genes - Softcover

Guttula, Satyavani

 
9783848483204: Insilico study of Type II Diabetes and Effective drugs: A Bioinformatics study of Diabetes genes
Softcover
ISBN 10: 3848483203 ISBN 13: 9783848483204
Verlag: LAP LAMBERT Academic Publishing, 2012

Inhaltsangabe

Diabetes is an important and increasingly common global health problem. The World Health Organization has estimated that about 170 million people currently have diabetes worldwide.Environmental factors such as obesity, a diet high in sugar, and a sedentary lifestyle are all risk factors for developing Type 2 diabetes. This book provides the basic knowledge to analyze Microarray data of diebetes. Clustering is done to the genes which are more expressed in Type II diabetes. Phylogenetic analysis is done on the basis of the sequence similarity by which the rate of expression is also similar. Two proteins Beliverdine and Uroporphyrinogen are taken and eight antidiabetic drugs such as Acarbose, Gliquidone, Metformin, Miglitol, Mitiglinide, Pioglitazone, Sitagliptin, Voglibose. These drugs are used as ligands. The two receptors are subjected to docking with eight ligands. ACARBOSE is determined as most efficient drug.

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Verlag
LAP LAMBERT Academic Publishing
Erscheinungsdatum
2012
Sprache
Englisch
ISBN 10 
3848483203
ISBN 13 
9783848483204
Einband
Taschenbuch
Anzahl der Seiten
128
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
Editions Muse
customerservice@vdm-vsg.de

Brivibas gatve 197
Riga
1039
Lettland