Verwandte Artikel zu Memory cells in diabetes: The effect of hyperglycemic...

Memory cells in diabetes: The effect of hyperglycemic memory on T- cells function - Softcover

Salman, Mohammed Ali; Sultan, Baqur A.; AL-Mosawi, Jaafar K.

 
9783848490752: Memory cells in diabetes: The effect of hyperglycemic memory on T- cells function
Softcover
ISBN 10: 3848490757 ISBN 13: 9783848490752
Verlag: LAP LAMBERT Academic Publishing, 2012

Inhaltsangabe

Antigen exposure is a strong stimulator of lymphocytes that triggers a variety of events including formation of cytokines such as interferon (IFN)-gamma (Cantrell, 1996), the defense against pathogen is impaired at high ambient osmolarity such as in the hyperosmolar renal medulla. Moreover, the immune response was reported to be impaired in diabetes Mellitus, which typically leads to increase of extracellular osmolarity,It cannot be excluded that "hyperglycemic memory" confounds the relationship between cell function and concomitant blood glucose concentration, i.e., hyperglycemia-induced changes in gene expression and biological reactions such as advanced glycation-end products in long-lived macromolecules may not be reversed when glycemia returns to normal, so that poor control is progressively "imprinted" on the cells , resulting in impairment of cellular immune activity.

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Verlag
LAP LAMBERT Academic Publishing
Erscheinungsdatum
2012
Sprache
Englisch
ISBN 10 
3848490757
ISBN 13 
9783848490752
Einband
Taschenbuch
Anzahl der Seiten
96
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
Alphascript Publishing
customerservice@vdm-vsg.de

Brivibas gatve 197
Riga
1039
Lettland