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Lung Cancer is a disease of uncontrolled cell growth and replication in lung tissues.These rapidly growing cells begin to invade adjacent tissues and thus lung cancer acts to be Metastatic in nature. This work aims to obtain a comparative and statistical collaboration of conserved mutated and unmutated patterns in lung cancer patients while highlighting RAS and EGFR Protein Families which are actively involved in the pathogenesis of Lung Cancer.A variety of bioinformatics tools and search engines were used to arrive at the sequence, structure and function of the proteins of these families. Inter protein analysis, Intra Protein analysis, conserved pattern identification, Mutation study, Protein-Protein interaction and Primer Designing were performed. On the basis of various parameters protein binding site was identified.Simulation was performed to get the optimized energy.The drug discovery program includes finding all chemical compounds having potential to inactive the protein.Virtual screening and docking studies were performed.The present study contributes to the possibility that genetic components are more important as compared to environmental and smoking(carcinogens) factors.
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Über die Autorin bzw. den Autor
Msc Bioinformatics,BIT,Mesra,India.Currently holds the position of Bioinformatics Research Associate in BioAxis DNA Research Centre,India.Several International publications in Bioinformatics field.Major research interest includes in-silico drug design,molecular modelling,simulation studies,toxicity prediction.
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Lung Cancer
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LAP LAMBERT Academic Publishing Apr 2012, 2012
ISBN 10: 3848498332
ISBN 13: 9783848498338
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Lung Cancer is a disease of uncontrolled cell growth and replication in lung tissues.These rapidly growing cells begin to invade adjacent tissues and thus lung cancer acts to be Metastatic in nature. This work aims to obtain a comparative and statistical collaboration of conserved mutated and unmutated patterns in lung cancer patients while highlighting RAS and EGFR Protein Families which are actively involved in the pathogenesis of Lung Cancer.A variety of bioinformatics tools and search engines were used to arrive at the sequence, structure and function of the proteins of these families. Inter protein analysis, Intra Protein analysis, conserved pattern identification, Mutation study, Protein-Protein interaction and Primer Designing were performed. On the basis of various parameters protein binding site was identified.Simulation was performed to get the optimized energy.The drug discovery program includes finding all chemical compounds having potential to inactive the protein.Virtual screening and docking studies were performed.The present study contributes to the possibility that genetic components are more important as compared to environmental and smoking(carcinogens) factors. 240 pp. Englisch. Bestandsnummer des Verkäufers 9783848498338
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Lung Cancer
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LAP LAMBERT Academic Publishing, 2012
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ISBN 13: 9783848498338
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Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Bhattacharya AnupamMsc Bioinformatics,BIT,Mesra,India.Currently holds the position of Bioinformatics Research Associate in BioAxis DNA Research Centre,India.Several International publications in Bioinformatics field.Major research in. Bestandsnummer des Verkäufers 5527225
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Lung Cancer | A Comparative Assessment of the Roles of RAS and EGFR Protein Families
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LAP LAMBERT Academic Publishing, 2012
ISBN 10: 3848498332
ISBN 13: 9783848498338
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Taschenbuch. Zustand: Neu. Lung Cancer | A Comparative Assessment of the Roles of RAS and EGFR Protein Families | Anupam Bhattacharya (u. a.) | Taschenbuch | 240 S. | Englisch | 2012 | LAP LAMBERT Academic Publishing | EAN 9783848498338 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. Bestandsnummer des Verkäufers 106437306
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Lung Cancer
Verlag:
LAP LAMBERT Academic Publishing Apr 2012, 2012
ISBN 10: 3848498332
ISBN 13: 9783848498338
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Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Lung Cancer is a disease of uncontrolled cell growth and replication in lung tissues.These rapidly growing cells begin to invade adjacent tissues and thus lung cancer acts to be Metastatic in nature. This work aims to obtain a comparative and statistical collaboration of conserved mutated and unmutated patterns in lung cancer patients while highlighting RAS and EGFR Protein Families which are actively involved in the pathogenesis of Lung Cancer.A variety of bioinformatics tools and search engines were used to arrive at the sequence, structure and function of the proteins of these families. Inter protein analysis, Intra Protein analysis, conserved pattern identification, Mutation study, Protein-Protein interaction and Primer Designing were performed. On the basis of various parameters protein binding site was identified.Simulation was performed to get the optimized energy.The drug discovery program includes finding all chemical compounds having potential to inactive the protein.Virtual screening and docking studies were performed.The present study contributes to the possibility that genetic components are more important as compared to environmental and smoking(carcinogens) factors.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 240 pp. Englisch. Bestandsnummer des Verkäufers 9783848498338
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Lung Cancer : A Comparative Assessment of the Roles of RAS and EGFR Protein Families
Verlag:
LAP LAMBERT Academic Publishing, 2012
ISBN 10: 3848498332
ISBN 13: 9783848498338
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Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Lung Cancer is a disease of uncontrolled cell growth and replication in lung tissues.These rapidly growing cells begin to invade adjacent tissues and thus lung cancer acts to be Metastatic in nature. This work aims to obtain a comparative and statistical collaboration of conserved mutated and unmutated patterns in lung cancer patients while highlighting RAS and EGFR Protein Families which are actively involved in the pathogenesis of Lung Cancer.A variety of bioinformatics tools and search engines were used to arrive at the sequence, structure and function of the proteins of these families. Inter protein analysis, Intra Protein analysis, conserved pattern identification, Mutation study, Protein-Protein interaction and Primer Designing were performed. On the basis of various parameters protein binding site was identified.Simulation was performed to get the optimized energy.The drug discovery program includes finding all chemical compounds having potential to inactive the protein.Virtual screening and docking studies were performed.The present study contributes to the possibility that genetic components are more important as compared to environmental and smoking(carcinogens) factors. Bestandsnummer des Verkäufers 9783848498338
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Lung Cancer: A Comparative Assessment of the Roles of RAS and EGFR Protein Families
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LAP LAMBERT Academic Publishing, 2012
ISBN 10: 3848498332
ISBN 13: 9783848498338
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Paperback. Zustand: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book. Bestandsnummer des Verkäufers ERICA79638484983326
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