Inhaltsangabe
Part I Overview.- Chapter 1. Metallomics: Integrated Biometal Science.- Part II Analytical techniques and strategies surrounding metallomics.- Chapter 2. Speciation and identification of chalcogen-containing metabolites.- Chapter 3. Visualization of intracellular elements using scanning X-ray fluorescence microscopy.- Chapter 4. Quantitative elemental bioimaging protocol using femtosecond-Laser Ablation-ICP-Mass Spectrometry coupled with glass standard material.- Chapter 5. Single cells analysis by using ICP-MS.- Chapter 6. Synchrotron radiation X-ray analysis of metal accumulating plants.- Chapter 7. 77Se NMR Spectroscopy for Speciation Analysis of Selenium Compounds.- Chapter 8. Protein quantification and quantitative phosphorylation analysis by the determination of hetero atoms (S and P) by means of nanoHPLC-ICPMS.- Chapter 9. Analysis of drug active pharmaceutical ingredients and bio-molecules using triple quadrupole ICP-MS.- Chapter 10. Highly sensitive analysis of proteins and metabolites by metal tagging using LC-ICP-MS.- Part III Application of metallomics in molecular biology, medicine and pharmaceutical sciences.- Chapter 11. Comprehensive element analysis of prokaryotic and eukaryotic cells as well as organelles by ICP-MS.- Chapter 12. Iron isotope signature for red blood cell samples from Japanese female donors of various ages.- Chapter 13. Roles of zinc transporters in cellular transport of cadmium and manganese.- Chapter 14. Link between metal homeostasis and neurodegenerative diseases: crosstalk of metals and amyloidogenic proteins at the synapse.- Chapter 15. New insight into metallomics in cognition.- Chapter 16. Frontier of development for metallodrugs on the basis of metallomic pharmacology and medicinal inorganic chemistry.
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