Drebrin: From Structure and Function to Physiological and Pathological Roles (Advances in Experimental Medicine and Biology, 1006, Band 1006) - Hardcover

Buch 308 von 544: Advances in Experimental Medicine and Biology
 
9784431565482: Drebrin: From Structure and Function to Physiological and Pathological Roles (Advances in Experimental Medicine and Biology, 1006, Band 1006)
Hardcover
ISBN 10: 4431565485 ISBN 13: 9784431565482
Verlag: Springer, 2017

Inhaltsangabe

This book is the first comprehensive review of drebrin, which plays pivotal roles in various cellular events, via forming unique actin cytoskeletons, including synapse formation and in synaptic function. Particularly the loss of drebrin from dendritic spines is used as a marker of dementia in neurological disorders such as Alzheimer’s disease. Since drebrin was first identified by our group in 1985, many studies of drebrin have been done in various fields, including not only molecular biology, biophysics, cell biology, neuroscience, clinical studies, spermatogenesis, immunology, and cancer metastasis, but others as well. The structure of this book facilitates the understanding of the whole picture of studies on drebrin. The volume begins with a general introduction to drebrin, and then the chapters in the second part provide the basic knowledge for further understanding. The third part examines its function in the nervous system, and the fourth part discusses its function in the non-nervous system. This work will appeal to researchers who are interested in cytoskeletal dynamics at membrane-cytoskeletal interface as well as the number of them who use drebrin as a tool, such as a marker of synaptic function or a disease marker. This volume is kept as concise as possible in order to be understood by readers in diverse scientific disciplines.

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Über die Autorin bzw. den Autor

Tomoaki Shirao, MD, PhD
Department of Neurobiology and Behavior
Gunma University Graduate School of Medicine
Gunma, Japan

Yuko Sekino, PhD
Division of Pharmacology
National Institute of Health Sciences
Tokyo, Japan

Von der hinteren Coverseite

This book is the first comprehensive review of drebrin, which plays pivotal roles in various cellular events, via forming unique actin cytoskeletons, including synapse formation and in synaptic function. Particularly the loss of drebrin from dendritic spines is used as a marker of dementia in neurological disorders such as Alzheimer’s disease. Since drebrin was first identified by our group in 1985, many studies of drebrin have been done in various fields, including not only molecular biology, biophysics, cell biology, neuroscience, clinical studies, spermatogenesis, immunology, and cancer metastasis, but others as well. The structure of this book facilitates the understanding of the whole picture of studies on drebrin. The volume begins with a general introduction to drebrin, and then the chapters in the second part provide the basic knowledge for further understanding. The third part examines its function in the nervous system, and the fourth part discusses its function in the non-nervous system. This work will appeal to researchers who are interested in cytoskeletal dynamics at membrane-cytoskeletal interface as well as the number of them who use drebrin as a tool, such as a marker of synaptic function or a disease marker. This volume is kept as concise as possible in order to be understood by readers in diverse scientific disciplines.

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Verlag
Springer
Erscheinungsdatum
2017
Sprache
Englisch
ISBN 10 
4431565485
ISBN 13 
9784431565482
Einband
Gebundene Ausgabe
Auflage
1
Anzahl der Seiten
413
Herausgeber
Shirao Tomoaki, Sekino Yuko
Kontakt zum Hersteller
ProductSafety@springernature.com
ProductSafety@springernature.com

Poststr. 9
Darmstadt
64293
Deutschland

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Vorgestellte Ausgabe

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Verlag: Springer, 2019
Softcover