Verwandte Artikel zu Nicotinoid Insecticides and the Nicotinic Acetylcholine...

Nicotinoid Insecticides and the Nicotinic Acetylcholine Receptor - Hardcover

 
9784431702139: Nicotinoid Insecticides and the Nicotinic Acetylcholine Receptor
Hardcover
ISBN 10: 443170213X ISBN 13: 9784431702139
Verlag: Springer, 1999

Inhaltsangabe

Insect pest control has continuously evolved from inorganics to botanicals, to chlo­ rinated hydrocarbons, to organophosphorus compounds and methylcarbamates, then synthetic pyrethroids and most recently synthetic nicotinoids as the major classes. These insecticides allowed high standards of crop protection at minimal cost. A limitation in each new class of compounds is the selection of resistant strains and ultimate control failures and this serves as a driving force to discover and develop replacement compounds to circumvent resistance and overcome problem areas. The nicotinoids now play a critical role in meeting this need. Three generations of chemicals are involved in the history of nicotinoid insecti­ cides. The first generation was the botanical nicotine used for at least three centuries to control sucking insect pests but largely replaced in the 1940s and 1950s by the more effective organophosphorus compounds and methylcarbamates, some with systemic properties. Synthesis programs based on nicotine as a prototype did not yield compounds that could compete with other synthetic insecticides. The second generation was the nitromethylene type such as nithiazine, discovered by Shell sci­ entists in a screening/optimization program. The nitromethylenes had the potency, selectivity, and systemic properties but lacked the field effectiveness largely because of photolability (so close yet so far from a major commercial product). The third generation required a series of advances made by Bayer researchers starting from nithiazine as the model and enhancing its photostability and potency with a nitroimine and chloropyridyl moiety, respectively, to give imidacloprid, the subject of much of this monograph.

Die Inhaltsangabe kann sich auf eine andere Ausgabe dieses Titels beziehen.

Von der hinteren Coverseite

Insect pest control has continuously evolved from inorganics to botanicals, to chlo­ rinated hydrocarbons, to organophosphorus compounds and methylcarbamates, then synthetic pyrethroids and most recently synthetic nicotinoids as the major classes. These insecticides allowed high standards of crop protection at minimal cost. A limitation in each new class of compounds is the selection of resistant strains and ultimate control failures and this serves as a driving force to discover and develop replacement compounds to circumvent resistance and overcome problem areas. The nicotinoids now play a critical role in meeting this need. Three generations of chemicals are involved in the history of nicotinoid insecti­ cides. The first generation was the botanical nicotine used for at least three centuries to control sucking insect pests but largely replaced in the 1940s and 1950s by the more effective organophosphorus compounds and methylcarbamates, some with systemic properties. Synthesis programs based on nicotine as a prototype did not yield compounds that could compete with other synthetic insecticides. The second generation was the nitromethylene type such as nithiazine, discovered by Shell sci­ entists in a screening/optimization program. The nitromethylenes had the potency, selectivity, and systemic properties but lacked the field effectiveness largely because of photolability (so close yet so far from a major commercial product). The third generation required a series of advances made by Bayer researchers starting from nithiazine as the model and enhancing its photostability and potency with a nitroimine and chloropyridyl moiety, respectively, to give imidacloprid, the subject of much of this monograph.

„Über diesen Titel“ kann sich auf eine andere Ausgabe dieses Titels beziehen.

Verlag
Springer
Erscheinungsdatum
1999
Sprache
Englisch
ISBN 10 
443170213X
ISBN 13 
9784431702139
Einband
Gebundene Ausgabe
Anzahl der Seiten
308
Herausgeber
Yamamoto I., Casida J.E.
Kontakt zum Hersteller
Springer Nature Customer Service Center GmbH
ProductSafety@springernature.com

Europaplatz 3
Heidelberg
69115
Deutschland