Modelling Atherosclerosis: Towards the Mathematical Prediction (Omn.Univ.Europ.) - Softcover

EL KHATIB, Nader

Softcover

ISBN 10: 6131527989 ISBN 13: 9786131527982

Verlag: Éditions universitaires européennes, 2010

Inhaltsangabe

Atherosclerosis is an inflammatory disease which starts when low density lipoproteins (LDL) enter the intima of blood vessel where they are oxidized (ox-LDL). The ox-LDL is considered as a dangerous agent by the immune system provoking an anti-inflammatory response. This immune response triggers the recruitment of monocytes into the intima where they differentiate into macrophages and foam cells. The latter amplifies the production of inflammatory cytokines and further recruitment of monocytes. This auto-amplified process is compensated by the secretion of anti-inflammatory cytokines biochemical anti-inflammation) and triggers the migration of smooth muscle cells to form a fibrous cap that covers the lipid core. These fibrous caps with the lipid core are called atherosclerosis plaque. It changes the geometry of the blood vessel by narrowing it and interacts with the blood flow. This interaction may have dangerous consequences related to the plaque rupture or to the formation of blood clot. This book is devoted to mathematical modelling ofthese phenomena.

Über diesen Titel

Über die Autorin bzw. den Autor

Nader El Khatib, PhD in applied mathematics, mathematical modelling and applications on biology and medicine,professor and researcher at the École Centrale de Lyon, France.

Details zur Ausgabe

• Verlag: Éditions universitaires européennes
• Erscheinungsdatum: 2010
• Sprache: Englisch
• ISBN 10: 6131527989
• ISBN 13: 9786131527982
• Einband: Taschenbuch
• Anzahl der Seiten: 96
• Kontakt zum Hersteller: Nicht verfügbar
• Verantwortliche Person: Editions Muse; customerservice@vdm-vsg.de; ; Brivibas gatve 197; Riga; 1039; Lettland