Design & Evaluation of Controlled Release Matrix Tablets of Prazosin: Modern Management of Hypertension - Softcover

Kothari, Rajan; Sharma, Gaurav Kumar; Atul Tiwari, Pankaj Chasta

 
9786138387824: Design & Evaluation of Controlled Release Matrix Tablets of Prazosin: Modern Management of Hypertension
Softcover
ISBN 10: 6138387821 ISBN 13: 9786138387824
Verlag: LAP LAMBERT Academic Publishing, 2018

Inhaltsangabe

In the present study, we have prepared matrix tablet formulations using Prazocin as a model drug and Ethyl Cellulose, Two grades of Hydroxy Propyl Methyl Cellulose- HPMC-K4M & HPMC-K100M as polymers in different ratios. The developed matrix tablets were evaluated for different physical-chemical evaluations like drug content, hardness, friability, swelling index etc. All the formulations had shown the results within prescribed limits. The In vitro drug release study indicates that formulation PCF-7 containing EC, HPMC K100M in 1:2 ratio shown good release pattern for 14 hours compares to other formulations. The short-term stability study proved no change in the formulation of ageing and it indicates good stability.

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Über die Autorin bzw. den Autor

Mr. Rajan Kothari, M.Pharm.(Pharmaceutics), Rajiv Gandhi University of Health Sciences, Bangalore, Karnataka, India. Assistant Professor at Faculty of Pharmaceutical Sciences, Mewar University, Gangrar, Chittorgarh-312901, Rajasthan, India

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Verlag
LAP LAMBERT Academic Publishing
Erscheinungsdatum
2018
Sprache
Englisch
ISBN 10 
6138387821
ISBN 13 
9786138387824
Einband
Taschenbuch
Anzahl der Seiten
76
Kontakt zum Hersteller
Nicht verfügbar
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Riga
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