The Enzymes in Synthesis of Chiral Bioactive Compounds - Softcover

Mahmoud Morsy Mohamed, Nesrin; Hamed Imam Ismael, Eman; Abdallah A. Yosef, Hisham

 
9786138912842: The Enzymes in Synthesis of Chiral Bioactive Compounds
Softcover
ISBN 10: 6138912845 ISBN 13: 9786138912842
Verlag: Scholars' Press, 2019

Inhaltsangabe

The administration of chiral compounds in an enantiomerically pure form, instead of racemic mixtures, become an important issue especially in the pharmaceutical and agrochemical industries due to the well established correlation between the biological activity and stereochemistry. Pure enantiomers could be formed by the asymmetric synthesis and /or the resolution of racemates. This could be achieved by the use of enzymes as chiral catalysts. The advantages of enzymes are their high stereo- (chiral), regio- (positional) and chemo- (functional group specific) selectivity. This selectivity offers several benefits like high catalytic efficiency, preservation of asymmetric centres, single step transformations, easier separation, mild operating conditions and fewer environmental problems. The organic reactions that are catalyzed by enzymes to give chiral bioactive organic compounds include, for example, reduction (e.g. by dehydrogenases, ketoreductases), oxidation (e.g. by monooxygenases, dioxygenases), hydrolytic (e.g. by lipases, esterases) reactions.

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Verlag
Scholars' Press
Erscheinungsdatum
2019
Sprache
Englisch
ISBN 10 
6138912845
ISBN 13 
9786138912842
Einband
Taschenbuch
Anzahl der Seiten
92
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
Fastbook Publishing
customerservice@vdm-vsg.de

Brivibas gatve 197
Riga
1039
Lettland