Inhaltsangabe
Aceclofenac can be successfully designed in tablets as sustained release formulation using melt granulation technique. The present study has demonstrated that stearic acid could be successfully employed as a meltable binder. It is worthy of mentioning that for controlling the release of poorly water-soluble drugs, the method is still advantageous.The prepared Aceclofenac compressed tablets were tested for weight variation, content uniformity, friability, tablet thickness and drug content and all the parameters were found to be within the Pharmacopoeial limits. In vitro drug dissolution tests were performed and dissolution profile of the selected batch was matched with that of standard release profile suggested by USP. Hence, the formulation was selected as optimized formulation. The tablets were further evaluated for studying the effect of storage temperature and pH on drug release. The release profiles show no significant difference in drug releases. This confirms the prepared tablets were robust.
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Über die Autorin bzw. den Autor
Prof.(Dr.) Suresh G. SudkeGaurishankar Education society, Satara college of pharmacy, Satara (Maharashtra) Prof.M.R.BhiseDr.Rajendra Gode college of Pharmacy, Malkapur (Maharashtra) Prof.Pramod V.BurakleDr.Rajendra Gode college of Pharmacy, Malkapur (Maharashtra)
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Design of Sustained Release Tablet Using Melt Granulating Techniques
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Aceclofenac can be successfully designed in tablets as sustained release formulation using melt granulation technique. The present study has demonstrated that stearic acid could be successfully employed as a meltable binder. It is worthy of mentioning that for controlling the release of poorly water-soluble drugs, the method is still advantageous.The prepared Aceclofenac compressed tablets were tested for weight variation, content uniformity, friability, tablet thickness and drug content and all the parameters were found to be within the Pharmacopoeial limits. In vitro drug dissolution tests were performed and dissolution profile of the selected batch was matched with that of standard release profile suggested by USP. Hence, the formulation was selected as optimized formulation. The tablets were further evaluated for studying the effect of storage temperature and pH on drug release. The release profiles show no significant difference in drug releases. This confirms the prepared tablets were robust. 72 pp. Englisch. Bestandsnummer des Verkäufers 9786138933601
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Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Sudke SureshProf.(Dr.) Suresh G. SudkeGaurishankar Education society, Satara college of pharmacy, Satara (Maharashtra) Prof.M.R.BhiseDr.Rajendra Gode college of Pharmacy, Malkapur (Maharashtra) Prof.Pramod V.BurakleDr.Rajendra Gode c. Bestandsnummer des Verkäufers 491562776
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Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Aceclofenac can be successfully designed in tablets as sustained release formulation using melt granulation technique. The present study has demonstrated that stearic acid could be successfully employed as a meltable binder. It is worthy of mentioning that for controlling the release of poorly water-soluble drugs, the method is still advantageous.The prepared Aceclofenac compressed tablets were tested for weight variation, content uniformity, friability, tablet thickness and drug content and all the parameters were found to be within the Pharmacopoeial limits. In vitro drug dissolution tests were performed and dissolution profile of the selected batch was matched with that of standard release profile suggested by USP. Hence, the formulation was selected as optimized formulation. The tablets were further evaluated for studying the effect of storage temperature and pH on drug release. The release profiles show no significant difference in drug releases. This confirms the prepared tablets were robust.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 72 pp. Englisch. Bestandsnummer des Verkäufers 9786138933601
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Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Aceclofenac can be successfully designed in tablets as sustained release formulation using melt granulation technique. The present study has demonstrated that stearic acid could be successfully employed as a meltable binder. It is worthy of mentioning that for controlling the release of poorly water-soluble drugs, the method is still advantageous.The prepared Aceclofenac compressed tablets were tested for weight variation, content uniformity, friability, tablet thickness and drug content and all the parameters were found to be within the Pharmacopoeial limits. In vitro drug dissolution tests were performed and dissolution profile of the selected batch was matched with that of standard release profile suggested by USP. Hence, the formulation was selected as optimized formulation. The tablets were further evaluated for studying the effect of storage temperature and pH on drug release. The release profiles show no significant difference in drug releases. This confirms the prepared tablets were robust. Bestandsnummer des Verkäufers 9786138933601
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Taschenbuch. Zustand: Neu. Design of Sustained Release Tablet Using Melt Granulating Techniques | Suresh Sudke (u. a.) | Taschenbuch | Englisch | 2021 | Scholars' Press | EAN 9786138933601 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu Print on Demand. Bestandsnummer des Verkäufers 120398785
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