Development & Characterization Of Ofloxacin & Prednisolone Loaded NLCs: A Nano-structured Lipid Carriers (NLCs) - Softcover

Sahai, Deeksha

Softcover

ISBN 10: 6139453348 ISBN 13: 9786139453344

Verlag: LAP LAMBERT Academic Publishing, 2019

Inhaltsangabe

The present study was designed to develop and characterize nanostructured lipid carriers (NLC) of Ofloxacin and Prednisolone for topical use in case of infections associated with inflammation. Ofloxacin was obtained as gift sample from Mankind Pharma Ltd, Vill Kyarta, P.O. Misserwal, Poonta Sahib, Sir Mour. H.P. Whereas Prednisolone was purchased from Yarrow chem., Mumbai. It was evaluated for its pre-formulation studies (organoleptic properties, melting point, solubility, compatibility, max. wavelength of absorption). In pre-formulation study, drugs were found having the similar properties as described in Indian Pharmacopoeia (IP) and United States Pharmacopoeia (USP). SEM photomicrograph revealed that NLCs were spherical with more or less smooth surface; particle size 512.3-1703 nm and PDI- 0.399-0.742 (ofloxacin) and particle size 539.3-1736.7 nm and PDI- 0.335 - 0.711 (prednisolone) etc. In conclusion, the prepared NLCs had prolonged release effects with good potential for topical delivery of NLC based gel formulation of ofloxacin & prednisolone.

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Über die Autorin bzw. den Autor

I am Deeksha Sahai native of Bareilly, Uttar Pradesh, India. I have been done M. Pharmacy (Pharmaceutics) from Faculty of Engineering and Technology, Department of Pharmacy, MJP Rohilkhand University, Bareilly. Currently working as Assistant Professor at Bareilly International University, Bareilly- 243006 (UP) India.

Details zur Ausgabe

• Verlag: LAP LAMBERT Academic Publishing
• Erscheinungsdatum: 2019
• Sprache: Englisch
• ISBN 10: 6139453348
• ISBN 13: 9786139453344
• Einband: Taschenbuch
• Anzahl der Seiten: 116
• Herausgeber: Singh Sobhna
• Kontakt zum Hersteller: Nicht verfügbar
• Verantwortliche Person: SIA OmniScriptum Publishing; customerservice@vdm-vsg.de; ; Brivibas gatve 197; Riga; 1039; Lettland