Optimisation of tablet: Formulation & optimisation of rosuvastatin tablet by complexation with cyclodextrin by spray drying method - Softcover

Kapse (Yelam), Vidya Nitin

 
9786139834358: Optimisation of tablet: Formulation & optimisation of rosuvastatin tablet by complexation with cyclodextrin by spray drying method
Softcover
ISBN 10: 613983435X ISBN 13: 9786139834358
Verlag: LAP LAMBERT Academic Publishing, 2018

Inhaltsangabe

The most important property of a dosage form is its ability to deliver the active ingredients to the site of action in an amount sufficient to elicit the desired pharmacological response. This property of the dosage form has been variously referred to its physiological availability, biological availability or bioavailability. "Bioavailability is defined more precisely as the rate and extent of absorption of a drug from its dosage form in to the systemic circulation". Many of the new drugs (APIs) exhibits low and variable dissolution and bioavailability due to their poor aqueous solubility at physiological pHs and consequent low dissolution rate. These drugs are classified as class II drugs under BCS classification. Biopharmaceutical Classification System (BCS) guidance was provided by USFDA to improve the efficiency of drug product development process in the BCS, drugs are grouped into four major classes basing on the solubility and permeability as follows: I. Class I (High solubility and High permeability) II. Class II (Low solubility and High permeability) III. Class III (high solubility and low permeability) IV. Class IV (Low solubility and Low permeability).

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Über die Autorin bzw. den Autor

Mrs. Vidya Nitin Kapse has completed her B.Pharm and M.Pharm (Pharmaceutics) from PDVVP College of Pharmacy, Ahmednagar, PUNE University. She has total 12 years of teaching experience at Shivlingeshwar College of Pharmacy Almala, Latur. Currently she is working as an Assistant Professor & Head Department of Pharmacy Practice at SCOP, Almala, India.

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Verlag
LAP LAMBERT Academic Publishing
Erscheinungsdatum
2018
Sprache
Englisch
ISBN 10 
613983435X
ISBN 13 
9786139834358
Einband
Taschenbuch
Anzahl der Seiten
100
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
Betascript Publishing
customerservice@vdm-vsg.de

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Riga
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