Inhaltsangabe
The present investigation was to formulation and development of fast dissolving mucoadhesive buccal film of nebivolol by using solvent casting method. Nebivolol is a third-generation cardio selective ß1-blocker undergoes extensive metabolism in the liver, gastrointestinal disturbance, abdominal pain after its oral administration and resulting in to a poor bioavailability (10-12%). In order to improve the bioavailability, efficacy and minimize the side effects associated with oral administration. Prepared mucoadhesive buccal films using HPMC E15 and PVP as mucoadhesive polymers. Among the two polymers HPMC E15 showed an increased in-vitro residence time due to high mucoadhesive property. Mucoadhesive buccal films were evaluated by weight variation, thickness, folding endurance, pH, in vitro disintegration, in vitro dissolution, tensile strength and drug content. In-vitro drug release study was showed more than 98.19±0.02% drug released within 40 min. The tensile strength of formulation SW9 was found 50.00 N/mm2. Thus it can concluded that the prepared formulation of buccal mucoadhesive film can be a novel treatment for myocardial infarction and angina pectoris.
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Über die Autorin bzw. den Autor
O Dr. Anilkumar J. Shinde, M.Pharm Ph.D (Farmácia) tem 26 anos de experiência no ensino e na investigação. Atualmente, trabalha como Professor Associado no Departamento de Farmácia da Faculdade de Farmácia Bharati Vidyapeeth, Kolhapur. Tem 66 trabalhos de investigação e 5 artigos de revisão publicados em revistas nacionais e internacionais. Uma patente nigeriana.
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Formulation, Design and Characterization of Mucoadhesive Buccal Film
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LAP LAMBERT Academic Publishing Mai 2018, 2018
ISBN 10: 6139848172
ISBN 13: 9786139848171
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The present investigation was to formulation and development of fast dissolving mucoadhesive buccal film of nebivolol by using solvent casting method. Nebivolol is a third-generation cardio selective beta1-blocker undergoes extensive metabolism in the liver, gastrointestinal disturbance, abdominal pain after its oral administration and resulting in to a poor bioavailability (10-12%). In order to improve the bioavailability, efficacy and minimize the side effects associated with oral administration. Prepared mucoadhesive buccal films using HPMC E15 and PVP as mucoadhesive polymers. Among the two polymers HPMC E15 showed an increased in-vitro residence time due to high mucoadhesive property. Mucoadhesive buccal films were evaluated by weight variation, thickness, folding endurance, pH, in vitro disintegration, in vitro dissolution, tensile strength and drug content. In-vitro drug release study was showed more than 98.19±0.02% drug released within 40 min. The tensile strength of formulation SW9 was found 50.00 N/mm2. Thus it can concluded that the prepared formulation of buccal mucoadhesive film can be a novel treatment for myocardial infarction and angina pectoris. 64 pp. Englisch. Bestandsnummer des Verkäufers 9786139848171
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Formulation, Design and Characterization of Mucoadhesive Buccal Film
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Formulation, Design and Characterization of Mucoadhesive Buccal Film
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Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Shinde AnilkumarDr. Anilkumar j Shinde M.Pharm Ph.D started his career in Pune university as Lecturer in Pharmaceutics & younged in teaching since 1994. Presently he is working as Associate Professor in Pharmaceutics Department. He i. Bestandsnummer des Verkäufers 385661865
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Formulation, Design and Characterization of Mucoadhesive Buccal Film
Verlag:
LAP LAMBERT Academic Publishing Mai 2018, 2018
ISBN 10: 6139848172
ISBN 13: 9786139848171
Neu
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Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The present investigation was to formulation and development of fast dissolving mucoadhesive buccal film of nebivolol by using solvent casting method. Nebivolol is a third-generation cardio selective ß1-blocker undergoes extensive metabolism in the liver, gastrointestinal disturbance, abdominal pain after its oral administration and resulting in to a poor bioavailability (10-12%). In order to improve the bioavailability, efficacy and minimize the side effects associated with oral administration. Prepared mucoadhesive buccal films using HPMC E15 and PVP as mucoadhesive polymers. Among the two polymers HPMC E15 showed an increased in-vitro residence time due to high mucoadhesive property. Mucoadhesive buccal films were evaluated by weight variation, thickness, folding endurance, pH, in vitro disintegration, in vitro dissolution, tensile strength and drug content. In-vitro drug release study was showed more than 98.19±0.02% drug released within 40 min. The tensile strength of formulation SW9 was found 50.00 N/mm2. Thus it can concluded that the prepared formulation of buccal mucoadhesive film can be a novel treatment for myocardial infarction and angina pectoris.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 64 pp. Englisch. Bestandsnummer des Verkäufers 9786139848171
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Formulation, Design and Characterization of Mucoadhesive Buccal Film : Buccal Film
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Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The present investigation was to formulation and development of fast dissolving mucoadhesive buccal film of nebivolol by using solvent casting method. Nebivolol is a third-generation cardio selective beta1-blocker undergoes extensive metabolism in the liver, gastrointestinal disturbance, abdominal pain after its oral administration and resulting in to a poor bioavailability (10-12%). In order to improve the bioavailability, efficacy and minimize the side effects associated with oral administration. Prepared mucoadhesive buccal films using HPMC E15 and PVP as mucoadhesive polymers. Among the two polymers HPMC E15 showed an increased in-vitro residence time due to high mucoadhesive property. Mucoadhesive buccal films were evaluated by weight variation, thickness, folding endurance, pH, in vitro disintegration, in vitro dissolution, tensile strength and drug content. In-vitro drug release study was showed more than 98.19±0.02% drug released within 40 min. The tensile strength of formulation SW9 was found 50.00 N/mm2. Thus it can concluded that the prepared formulation of buccal mucoadhesive film can be a novel treatment for myocardial infarction and angina pectoris. Bestandsnummer des Verkäufers 9786139848171
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Formulation, Design and Characterization of Mucoadhesive Buccal Film | Buccal Film
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Taschenbuch. Zustand: Neu. Formulation, Design and Characterization of Mucoadhesive Buccal Film | Buccal Film | Anilkumar Shinde (u. a.) | Taschenbuch | 64 S. | Englisch | 2018 | LAP LAMBERT Academic Publishing | EAN 9786139848171 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu. Bestandsnummer des Verkäufers 114003194
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