NRF2 is a master regulator of the anti-oxidative stress response through controlling the expression of anti-oxidative stress response proteins and detoxifying enzymes. Cancer cells also exploit NRF2 protective functions to thrive and resist anti-tumor drugs. NRF2 is highly active in several types of human cancers and is associated with aggressiveness and metastasis. NRF2 affects many targets that are involved in hypoxia, angiogenesis, invasion, drug resistance, and epithelial-mesenchymal transition. NRF2 was found to be targeted by many microRNAs, so that it could be used as effective cancer therapy to improve the outcomes and contribute to the advancement of anti-tumor drugs.
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Heba Kamal Nabih Hanafi- A Researcher at Medical Biochemistry Department- Medical Research Division- National Research Centre- Dokki, Giza -Egypt. Ph.D in Biochemistry (2017) - Biochemistry Department- Faculty of Science- Ain Shams University- Cairo- Egypt.
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Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Nabih Heba KamalHeba Kamal Nabih Hanafi- A Researcher at Medical Biochemistry Department- Medical Research Division- National Research Centre- Dokki, Giza -Egypt. Ph.D in Biochemistry (2017) - Biochemistry Department- Faculty of Scie. Bestandsnummer des Verkäufers 262744346
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Taschenbuch. Zustand: Neu. NRF2 as a Central Point in Cancer Metastasis | Heba Kamal Nabih | Taschenbuch | 60 S. | Englisch | 2019 | LAP LAMBERT Academic Publishing | EAN 9786139967148 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu. Bestandsnummer des Verkäufers 115186048
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