FORMULATION AND EVALUATION OF SIMVASTATIN TABLET: FAST DISSOLVING TABLET - Softcover

PATEL, URVASHI; PATEL, HARSHIL

Softcover

ISBN 10: 6200539138 ISBN 13: 9786200539137

Verlag: LAP LAMBERT Academic Publishing, 2020

Inhaltsangabe

To obtain an enhanced in-vitro dissolution rate of simvastatin by using Liquisolid technique and Liquisolid tablets were optimized by DoE approach 32 full factorial design using Design Expert Software.The liquisolid tablets were formulated by using propylene glycol (PG), as liquid vehicle, Avicel PH-102 as a carrier material, Aerosil as a coating material, and aspartame as sweetener and Kyron 314 as a superdisintegrant. The new mathematical model 32 full factorial design was utilized to formulate various liquisolid powder systems and to calculate amount of carrier material and coating material.Simvasatin Liquisolid compacts enhance aqueous solubility and dissolution rate in compare to other solubility enhancement technique. Hence, this research work may be useful to formulate fast disintegrating Tablets using Liquisolid Technique which may give rapid onset of action by rapid absorption, maximize efficacy, reduce dose and dose frequency & hence increase patient Compliance.

Über diesen Titel

Über die Autorin bzw. den Autor

Ms.Urvashi B Patel PhD Scholar in Pharmaceutics at JJTU, Rajastan. She has completed her M.Pharm (Pharmaceutics) from Gujarat Technological University. She has a 2.7 year experience as Assistant Professor at Shree Dhanvantary College of Pharmcy. She has an attended 7 Conferences. She has 14 National/International Publication.

Details zur Ausgabe

• Verlag: LAP LAMBERT Academic Publishing
• Erscheinungsdatum: 2020
• Sprache: Englisch
• ISBN 10: 6200539138
• ISBN 13: 9786200539137
• Einband: Taschenbuch
• Anzahl der Seiten: 124
• Kontakt zum Hersteller: Nicht verfügbar
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