Simultaneous Determinations of Some Drugs: Development and Validation of New Methods for Simultaneous Spectrophotometric Determination of Tetracycline, Doxycycline - Softcover

Al-Khalisy, Rokayia

Softcover

ISBN 10: 620235657X ISBN 13: 9786202356572

Verlag: Noor Publishing, 2018

Inhaltsangabe

A simple, sensitive, accurate and low cost effective spectrophotometric method has been developed for the determination of Tetracycline, Doxycycline and methyldopa in pure and pharmaceutical formulations. The method is based on the reaction of methyldopa with 4-aminoantipyren (4-AAP) in presence of potassium ferriecyanide (PFC) in an alkaline medium. Two optimization methods were applied to determine the optimum conditions of oxidizing coupling reaction variables; univariate and design of experiment (DOE) method. The conditions effecting the reaction; pH, buffer Volume, reagent concentration, oxidant concentration, type of buffer, order of addition, time of reaction and stability were optimized. The method was successfully applied to the analysis of the some drug tablets formulation.

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Über die Autorin bzw. den Autor

Rokayia S. Al-Kalissy:Ph.D. of Analytical Chemistry , M. Sc. Of Physical Chemistry, B.Sc. of Chemistry Science ( all from Baghdad University) wark as instructor in Chemistry Department, College of Education for Pure Science- Ibn Al-Haitham, University of Baghdad.

Details zur Ausgabe

• Verlag: Noor Publishing
• Erscheinungsdatum: 2018
• Sprache: Englisch
• ISBN 10: 620235657X
• ISBN 13: 9786202356572
• Einband: Taschenbuch
• Anzahl der Seiten: 272
• Kontakt zum Hersteller: Nicht verfügbar
• Verantwortliche Person: Editions universitaires europeennes; customerservice@vdm-vsg.de; ; Brivibas gatve 197; Riga; 1039; Lettland