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Pinaverium sustained release matrix tablets for colonic drug delivery - Softcover

Jha, Sajal Kumar; Rakasi, Sushma

 
9786202554589: Pinaverium sustained release matrix tablets for colonic drug delivery
Softcover
ISBN 10: 6202554584 ISBN 13: 9786202554589
Verlag: LAP LAMBERT Academic Publishing, 2020

Inhaltsangabe

This book deals with the Development and Characterization of sustained matrix tablets of a novel drug Pinaverium using different polymers.To facilitate the pH-independent drug release of Pinaverium, pH modifying agents (buffering agents) were used. Colon targeted tablets were prepared in two steps. Initially core tablets were prepared then the tablets were coated with Ph dependent polymers. Eudragit RLPO and S100 were used as enteric coating polymers. The pre-compression mixture of all formulations was subjected to various flow property tests and each one the formulations were passed the tests. The tablets were coated by polymers and so the coated tablets were subjected to various evaluation techniques. The tablets were passed all the tests. Among all the formulations F6 formulation was found to be optimized as a result of it had the drug release of up to 12 hours and showed most of 98.45% drug release.

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Über die Autorin bzw. den Autor

Dr. Sajal Kumar Jha, working as Head of The Department, School of Pharmaceutical Technology, ADAMAS University, Kolkata, obtained his B. Pharm & M.Pharm from RGUHS, Karnataka & Ph.D in Pharmaceutical Sciences from JNTU University Hyderabad.

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Verlag
LAP LAMBERT Academic Publishing
Erscheinungsdatum
2020
Sprache
Englisch
ISBN 10 
6202554584
ISBN 13 
9786202554589
Einband
Taschenbuch
Anzahl der Seiten
68
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Verantwortliche Person
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