The human kinome contains 518 proteins. They share a common mechanism of protein phosphorylation known to play an important role in cellular signaling pathways. Impaired kinase function is recognized to be involved in severe diseases like cancer. The challenge of this PhD work is the in silico identification of potentially interesting molecules concerning the inhibitory process of a set of protein kinases, namely PIM1, PIM2, CDC7, DRAK2 and CAMKIIδ. The faculty of this protein to interact in differentiation, proliferation and tissue repair phenomena makes their inhibitions crucial for treatments against tumor development in which they are involved. Despites their interests, until now there is no molecule acting on theses kinases has been proven by the Food and Drug Administration. In this way, the authors will focus, in this book on several in silico methods for rational drug design of new kinases inhibitors.
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Dr. Adnane Aouidate holds a PhD in Computer Aided Drug Design from Moulay Ismail University, Morocco, and worked in China as a postdoctoral researcher in the same field in Shenzhen Institute of Advanced Technology.
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The human kinome contains 518 proteins. They share a common mechanism of protein phosphorylation known to play an important role in cellular signaling pathways. Impaired kinase function is recognized to be involved in severe diseases like cancer. The challenge of this PhD work is the in silico identification of potentially interesting molecules concerning the inhibitory process of a set of protein kinases, namely PIM1, PIM2, CDC7, DRAK2 and CAMKIId. The faculty of this protein to interact in differentiation, proliferation and tissue repair phenomena makes their inhibitions crucial for treatments against tumor development in which they are involved. Despites their interests, until now there is no molecule acting on theses kinases has been proven by the Food and Drug Administration. In this way, the authors will focus, in this book on several in silico methods for rational drug design of new kinases inhibitors. 144 pp. Englisch. Bestandsnummer des Verkäufers 9786202789363
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Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The human kinome contains 518 proteins. They share a common mechanism of protein phosphorylation known to play an important role in cellular signaling pathways. Impaired kinase function is recognized to be involved in severe diseases like cancer. The challenge of this PhD work is the in silico identification of potentially interesting molecules concerning the inhibitory process of a set of protein kinases, namely PIM1, PIM2, CDC7, DRAK2 and CAMKIId. The faculty of this protein to interact in differentiation, proliferation and tissue repair phenomena makes their inhibitions crucial for treatments against tumor development in which they are involved. Despites their interests, until now there is no molecule acting on theses kinases has been proven by the Food and Drug Administration. In this way, the authors will focus, in this book on several in silico methods for rational drug design of new kinases inhibitors. Bestandsnummer des Verkäufers 9786202789363
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Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Aouidate AdnaneDr. Adnane Aouidate holds a PhD in Computer Aided Drug Design from Moulay Ismail University, Morocco, and worked in China as a postdoctoral researcher in the same field in Shenzhen Institute of Advanced Technology. Bestandsnummer des Verkäufers 452564577
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Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The human kinome contains 518 proteins. They share a common mechanism of protein phosphorylation known to play an important role in cellular signaling pathways. Impaired kinase function is recognized to be involved in severe diseases like cancer. The challenge of this PhD work is the in silico identification of potentially interesting molecules concerning the inhibitory process of a set of protein kinases, namely PIM1, PIM2, CDC7, DRAK2 and CAMKII¿. The faculty of this protein to interact in differentiation, proliferation and tissue repair phenomena makes their inhibitions crucial for treatments against tumor development in which they are involved. Despites their interests, until now there is no molecule acting on theses kinases has been proven by the Food and Drug Administration. In this way, the authors will focus, in this book on several in silico methods for rational drug design of new kinases inhibitors.Books on Demand GmbH, Überseering 33, 22297 Hamburg 144 pp. Englisch. Bestandsnummer des Verkäufers 9786202789363
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Taschenbuch. Zustand: Neu. Modeling of Kinases Inhibitors : 3D-QSAR, Moecular Docking and ADMET | Modeling of Organic Bioactive Molecules Using 3D-QSAR Analysis, Moecular Docking and Preliminary ADMET Evaluation | Adnane Aouidate (u. a.) | Taschenbuch | Englisch | 2020 | Noor Publishing | EAN 9786202789363 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. Bestandsnummer des Verkäufers 119071794
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