Quantification of DNA and AgNORs: correlating to cyclin D1-immunoexpression in human breast cancer - Softcover

Assem Hamed, Mahmoud

Softcover

ISBN 10: 6204725416 ISBN 13: 9786204725413

Verlag: LAP LAMBERT Academic Publishing, 2021

Inhaltsangabe

Assessment of cell proliferation through the evaluation of cyclin D1, AgNORs, and DNA content provides a promising approach to the prognosis of breast cancer. Therefore, this work aimed to evaluate the prognostic significance of AgNORs and DNA image cytometry, and their relation to cyclin D1 immunoreactivity in breast cancer. This study was carried out on 50 prospective biopsies taken from patients with breast tumor. They were divided into control (10 cases) and benign (10 cases) as well as malignant (30 cases) groups. Computer-assisted image analysis cytometry is applied to evaluate the count of positive reactions of AgNORs and cyclin D1, and an integrated optical density (IOD) technique is used to quantify DNA content in the tissues stained by Feulgen stain and to assess the density of cyclin D1 immunoreactivity.

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Über die Autorin bzw. den Autor

Mi nombre es Mahmoud Assem Hamed. He publicado muchos artículos de investigación en revistas internacionales revisadas por pares. Mi trabajo se centra principalmente en la biología del cáncer, con especial énfasis en el cáncer de mama. Me interesa la terapia dirigida y la investigación traslacional para desarrollar un tratamiento personalizado para cada caso individual.

Details zur Ausgabe

• Verlag: LAP LAMBERT Academic Publishing
• Erscheinungsdatum: 2021
• Sprache: Englisch
• ISBN 10: 6204725416
• ISBN 13: 9786204725413
• Einband: Taschenbuch
• Anzahl der Seiten: 52
• Kontakt zum Hersteller: Nicht verfügbar
• Verantwortliche Person: SIA OmniScriptum Publishing; customerservice@vdm-vsg.de; ; Brivibas gatve 197; Riga; 1039; Lettland