VALIDATION OF SPECTROPHOTOMETRIC METHODS: VALIDATION OF SPECTROPHOTOMETRIC METHODS FOR SIMULTANEOUS ESTIMATION IN COMBINED DOSAGE FORM - Softcover

Shinde, Anilkumar; More, Harinath; Tamboli, Firoj

 
9786205498910: VALIDATION OF SPECTROPHOTOMETRIC METHODS: VALIDATION OF SPECTROPHOTOMETRIC METHODS FOR SIMULTANEOUS ESTIMATION IN COMBINED DOSAGE FORM
Softcover
ISBN 10: 620549891X ISBN 13: 9786205498910
Verlag: LAP LAMBERT Academic Publishing, 2022

Inhaltsangabe

Two simple, accurate and reproducible spectrophotometric methods have been developed for the simultaneous estimation of Norfloxacin and Tinidazole in pharmaceutical dosage forms. The first method involves determination using the AUC Method (Area Under Curve Method); the sampling wavelengths selected are 272-282 nm and 313-323 nm over the concentration ranges of 2-12μg/mL and 3-18 μg/mL for Norfloxacin and Tinidazole respectively. The second method involves determination using the Q-Analysis Method (Absorbance Ratio Method); the sampling wavelengths selected are 277 nm and 318 nm over the concentration ranges of 2-12 μg/mL and 3-18 μg/mL for Norfloxacin and Tinidazole respectively. The results of the analysis were validated statistically and recovery studies were carried out as per ICH guidelines.

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Verlag
LAP LAMBERT Academic Publishing
Erscheinungsdatum
2022
Sprache
Englisch
ISBN 10 
620549891X
ISBN 13 
9786205498910
Einband
Tapa blanda
Anzahl der Seiten
56
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