DEVELOPMENT AND VALIDATION OF HPLC METHOD OF ROSUVASTATIN SODIUM: Analytical method of Rosuvastatin Sodium - Softcover

Verma, Prabhakar

Softcover

ISBN 10: 6206146502 ISBN 13: 9786206146506

Verlag: LAP LAMBERT Academic Publishing, 2023

Inhaltsangabe

For the analysis of Rosuvastatin calcium, a specific and uncomplicated HPLC method was devised and validated. Rosuvastatin calcium belongs to the statin family, which is a reductase inhibitor for 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA). The medication is used to treat hypertension and ischemic coronary artery disease. It is also used to treat dyslipidemia and aid in the reduction of "bad cholesterol" levels. The technique was carried out on a C18 Column (250 4.6mm 1.d; 5) in isocratic mode with the mobile phase acetonitrile and water in the ratio 75:25 v/v. The wavelength is 242 nm, and the flow rate is 0.6 milliliters per minute.The linearity was discovered between 10 and 60µg/ml, with a correlation coefficient of 0.9998. The medication has a 3.643 retention time. Because the suggested method is simple, quick, accurate, precise, and repeatable, it can be used for routine quality control analysis of rosuvastatin in both pure and tablet dosage forms.

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Über die Autorin bzw. den Autor

O Dr. Prabhakar Kumar Verma trabalha como Professor Associado de Química Farmacêutica desde há quinze anos no Departamento de Ciências Farmacêuticas da Universidade M.D. de Rohtak, Haryana. Supervisionou programas de mestrado e doutoramento em química farmacêutica e tem uma boa experiência na indústria.

Details zur Ausgabe

• Verlag: LAP LAMBERT Academic Publishing
• Erscheinungsdatum: 2023
• Sprache: Englisch
• ISBN 10: 6206146502
• ISBN 13: 9786206146506
• Einband: Taschenbuch
• Anzahl der Seiten: 56
• Kontakt zum Hersteller: Nicht verfügbar
• Verantwortliche Person: Editions Vie; customerservice@vdm-vsg.de; ; Brivibas gatve 197; Riga; 1039; Lettland