Inhaltsangabe
Smoking control is one of the biggest challenges for public health promotion, as it is responsible for high mortality rates which could be avoided. Studies show that the components derived from cigarette combustion cause epigenetic changes, such as methylation of the DNA molecule. This alteration causes gene silencing, resulting in a lack of gene expression and contributing to the phenotypic expression of various diseases, especially cancers, cardiovascular and lung diseases. Telomeres, on the other hand, are DNA-protein complexes that promote genome stability. They are located at the ends of eukaryotic chromosomes and in humans are represented by repetitive sequences of 6 nucleotides (TTAGGG)n. Telomere shortening occurs with each cell replication and this reduction leads to cellular senescence and apoptosis. Oxidative stress is one of the factors that accelerates telomere shortening and tobacco smoking contributes to this stress. Studies show a clear correlation between tobacco consumption, oxidative stress, early telomere shortening and inadequate DNA methylation.
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Über die Autorin bzw. den Autor
Paulo Roberto Queiroz - Possui graduação (Bacharelado e Licenciatura)em Ciências Biológicas pela Universidade de Brasília (1996); mestradoem Biologia Molecular (2000) e doutorado em Biologia Animal pelaUniversidade de Brasília (2006); e pós-doutorado em Genética Molecular.Leonardo Sphair e Milena Simas - Biomédicos - UniCEUB.
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Effects of cigarette components on the DNA molecule
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ISBN 10: 6207329678
ISBN 13: 9786207329670
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Effects of cigarette components on the DNA molecule
Verlag:
Our Knowledge Publishing Mär 2024, 2024
ISBN 10: 6207329678
ISBN 13: 9786207329670
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Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Smoking control is one of the biggest challenges for public health promotion, as it is responsible for high mortality rates which could be avoided. Studies show that the components derived from cigarette combustion cause epigenetic changes, such as methylation of the DNA molecule. This alteration causes gene silencing, resulting in a lack of gene expression and contributing to the phenotypic expression of various diseases, especially cancers, cardiovascular and lung diseases. Telomeres, on the other hand, are DNA-protein complexes that promote genome stability. They are located at the ends of eukaryotic chromosomes and in humans are represented by repetitive sequences of 6 nucleotides (TTAGGG)n. Telomere shortening occurs with each cell replication and this reduction leads to cellular senescence and apoptosis. Oxidative stress is one of the factors that accelerates telomere shortening and tobacco smoking contributes to this stress. Studies show a clear correlation between tobacco consumption, oxidative stress, early telomere shortening and inadequate DNA methylation.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 52 pp. Englisch. Bestandsnummer des Verkäufers 9786207329670
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Effects of cigarette components on the DNA molecule : DNA, telomeres and methylation
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Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Smoking control is one of the biggest challenges for public health promotion, as it is responsible for high mortality rates which could be avoided. Studies show that the components derived from cigarette combustion cause epigenetic changes, such as methylation of the DNA molecule. This alteration causes gene silencing, resulting in a lack of gene expression and contributing to the phenotypic expression of various diseases, especially cancers, cardiovascular and lung diseases. Telomeres, on the other hand, are DNA-protein complexes that promote genome stability. They are located at the ends of eukaryotic chromosomes and in humans are represented by repetitive sequences of 6 nucleotides (TTAGGG)n. Telomere shortening occurs with each cell replication and this reduction leads to cellular senescence and apoptosis. Oxidative stress is one of the factors that accelerates telomere shortening and tobacco smoking contributes to this stress. Studies show a clear correlation between tobacco consumption, oxidative stress, early telomere shortening and inadequate DNA methylation. Bestandsnummer des Verkäufers 9786207329670
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Taschenbuch. Zustand: Neu. Effects of cigarette components on the DNA molecule | DNA, telomeres and methylation | Paulo Roberto Queiroz (u. a.) | Taschenbuch | Englisch | 2024 | Our Knowledge Publishing | EAN 9786207329670 | Verantwortliche Person für die EU: SIA OmniScriptum Publishing, Brivibas Gatve 197, 1039 RIGA, LETTLAND, customerservice[at]vdm-vsg[dot]de | Anbieter: preigu. Bestandsnummer des Verkäufers 128838531
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