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DEVELOPMENT AND VALIDATION OF ALLOPURINOL: DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR ESTIMATION OF ALLOPURINOL IN BULK DRUG - Softcover

Rani, P. Sudha; Pragathi Bn, Vennila J; T. Srinivasa Reddy, Kavya T

 
9786207647019: DEVELOPMENT AND VALIDATION OF ALLOPURINOL: DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR ESTIMATION OF ALLOPURINOL IN BULK DRUG
Softcover
ISBN 10: 6207647017 ISBN 13: 9786207647019
Verlag: LAP LAMBERT Academic Publishing, 2024

Inhaltsangabe

The study is focused to develop and validate HPLC methods for estimation of Allopurinol in tablet dosage form. For routine analytical purpose it is desirable to establish methods capable of analysing huge number of samples in a short time with good robustness, accuracy and precision without any prior separation steps. HPLC method generates large amount of quality data, which serve as highly powerful and convenient analytical tool. The method shows good reproducibility and good recovery. From the specificity studies, it was found that the developed methods were specific for Allopurinol. The proposed methods were found to be simple, sensitive, accurate and precise and showed no interference from the common additives and excipients. The developed method was validated in terms of linearity, accuracy, precision in accordance with the ICH guidelines. Hence the proposed methods can be routinely used for the estimation of Allopurinol in bulk and pharmaceutical dosage forms.

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Über die Autorin bzw. den Autor

P.Sudha Rani est titulaire d'une maîtrise en sciences de la vie et d'un doctorat spécialisé en endocrinologie de l'université Sardar Patel, Gujarat. Elle a plus de 20 ans d'expérience dans l'enseignement. Ses domaines d'intérêt sont l'immunologie, la biotechnologie animale et la biotechnologie médicale. Elle a guidé de nombreux étudiants en maîtrise, en master et en doctorat.

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Verlag
LAP LAMBERT Academic Publishing
Erscheinungsdatum
2024
Sprache
Englisch
ISBN 10 
6207647017
ISBN 13 
9786207647019
Einband
Taschenbuch
Anzahl der Seiten
60
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
SIA OmniScriptum Publishing
customerservice@vdm-vsg.de

Brivibas gatve 197
Riga
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Lettland