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HIF-1 AS A POTENTIAL DRUG TARGET FOR SOLID TUMORS: DE - Softcover

Manohar, Sonal; Majithiya, Kinjal; Guralwar, Palak

 
9786208010676: HIF-1 AS A POTENTIAL DRUG TARGET FOR SOLID TUMORS: DE
Softcover
ISBN 10: 6208010675 ISBN 13: 9786208010676
Verlag: LAP LAMBERT Academic Publishing, 2024

Inhaltsangabe

Hypoxia is a typical microenvironmental characteristic of many solid tumors. HIF-1 is the key regulator of growing tumor's response to hypoxia. HIF-1α subunit levels rise in hypoxic environments, when oncogenes are activated, and/or when tumor suppressor genes are inactivated, this is necessary for HIF-1 function in tumors. HIF-1 turns on genes that enable cells of a solid tumor to flourish in the noxious hypoxic tumor environment via attainment of numerous cancer hallmarks. This book elaborates the regulation and role of HIF-1 in oncogenic signalling. Further, its potential as a drug target for solid tumors is also discussed. The book will be useful as a reference book for students of graduate and post-graduate level courses in Life Science, Biomedical Science as well as to those who have a special interest in Cancer Biology.

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Über die Autorin bzw. den Autor

Dr. Sonal Manohar is currently working as an Assistant Professor at the Department of Biological Sciences, Sunandan Divatia School of Science, SVKM's NMIMS (Deemed-to-be) University, Mumbai, India. Her main research area is translational cancer research with a special focus on cell signaling.

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Verlag
LAP LAMBERT Academic Publishing
Erscheinungsdatum
2024
Sprache
Englisch
ISBN 10 
6208010675
ISBN 13 
9786208010676
Einband
Taschenbuch
Anzahl der Seiten
100
Kontakt zum Hersteller
SIA OmniScriptum Publishing
customerservice@vdm-vsg.de

Brivibas gatve 197
Riga
1039
Lettland