Verwandte Artikel zu Mechanisms, Risk Factors, and Treatment Strategies...

Mechanisms, Risk Factors, and Treatment Strategies for Osteoporosis: Mechanisms, Risk Factors, and Treatment Strategies for Osteoporosis - Softcover

El-Banna, Mona

 
9786208429102: Mechanisms, Risk Factors, and Treatment Strategies for Osteoporosis: Mechanisms, Risk Factors, and Treatment Strategies for Osteoporosis
Softcover
ISBN 10: 6208429102 ISBN 13: 9786208429102
Verlag: LAP LAMBERT Academic Publishing, 2025

Inhaltsangabe

Osteoporosis is a systemic skeletal disorder characterized by reduced bone mass and microarchitectural deterioration, leading to increased fracture risk. Multiple factors contribute to its pathogenesis, including hormonal deficiencies (estrogen, testosterone, and growth hormone), metabolic imbalances, chronic inflammation, glucocorticoid therapy, and lifestyle-related influences. Glucocorticoids (GCs) play a significant role in osteoporosis by inhibiting osteoblast differentiation, promoting osteoclast activity via the RANKL-OPG pathway, impairing calcium absorption, and disrupting vitamin D metabolism. Additionally, inflammatory cytokines, growth factors, and prostanoids influence bone remodeling, further exacerbating bone loss. Management strategies include lifestyle modifications, adequate calcium and vitamin D intake, pharmacologic interventions (bisphosphonates, SERMs, PTH analogs, and monoclonal antibodies), and hormone replacement therapy where applicable. Early detection and intervention are essential to prevent fractures and maintain skeletal health.

Die Inhaltsangabe kann sich auf eine andere Ausgabe dieses Titels beziehen.

Über die Autorin bzw. den Autor

Mona Anwar Mohamed El-Bana, Professor at the National Research Centre, advances medical biochemistry through research and teaching. Her work focuses on disease mechanisms, metabolic disorders, and neurodegeneration. She mentors students, contributes to scientific knowledge, and bridges research with clinical applications for improved healthcare.

„Über diesen Titel“ kann sich auf eine andere Ausgabe dieses Titels beziehen.

Verlag
LAP LAMBERT Academic Publishing
Erscheinungsdatum
2025
Sprache
Englisch
ISBN 10 
6208429102
ISBN 13 
9786208429102
Einband
Taschenbuch
Anzahl der Seiten
88
Kontakt zum Hersteller
Nicht verfügbar
Verantwortliche Person
SIA OmniScriptum Publishing
customerservice@vdm-vsg.de

Brivibas gatve 197
Riga
1039
Lettland