Biological Roles of Fatty Acids in Health and Disease: Biological Roles of Fatty Acids in Health and Disease - Softcover

El-Banna, Mona; Hassan, Heba

 
9786209574498: Biological Roles of Fatty Acids in Health and Disease: Biological Roles of Fatty Acids in Health and Disease

Inhaltsangabe

Omega-3 and omega-6 polyunsaturated fatty acids (PUFAs) are essential dietary lipids that play central roles in cellular structure, metabolic regulation, immune function, and inflammatory signaling. Over recent decades, extensive experimental and clinical research has clarified the mechanisms through which these fatty acids influence human health and disease. This book provides an integrative overview of the physiological and pathological roles of omega-3 PUFAs-particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)-while also addressing the complex, context-dependent effects of omega-6 fatty acids.Omega-3 PUFAs act as key modulators of inflammation by inhibiting NF-¿B signaling, regulating cytokine production, remodeling membrane lipid composition, and generating specialized pro-resolving mediators. Beyond anti-inflammatory actions, they influence mTOR signaling, mitochondrial function, oxidative balance, T-cell differentiation, endothelial activity, and gene expression. These molecular effects translate into clinically meaningful benefits across autoimmune, cardiovascular, metabolic, oncologic, and neurodegenerative disorders.

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Über die Autorin bzw. den Autor

Mona Anwar Mohamed El-Banna, Professor at the National Research Centre, advances medical biochemistry through research and teaching. Her work focuses on disease mechanisms, metabolic disorders, and neurodegeneration. She mentors students, contributes to scientific knowledge, and bridges research with clinical applications for improved healthcare.

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