IN SILICO AND IN VITRO ALDOSE REDUCTASE INHIBITION OF FLAVONOIDS: IN SILICO AND IN VITRO ALDOSE REDUCTASE INHIBITORY ACTIVITY OF SOME SYNTHESIZED FLAVONOID DERIVATIVES - Softcover

Vijayabaskaran, M.; Kape Meyar, E.; Madeswaran, A.

 
9786209863264: IN SILICO AND IN VITRO ALDOSE REDUCTASE INHIBITION OF FLAVONOIDS: IN SILICO AND IN VITRO ALDOSE REDUCTASE INHIBITORY ACTIVITY OF SOME SYNTHESIZED FLAVONOID DERIVATIVES
Softcover
ISBN 10: 6209863264 ISBN 13: 9786209863264
Verlag: LAP LAMBERT Academic Publishing, 2026

Inhaltsangabe

Cataracts are one of the primary causes of visual impairment in diabetics. Patients with diabetes mellitus are said to be five times more likely to acquire cataracts, particularly if they begin the condition early. Flavonoids are bioactive secondary metabolites of plants that belong to a large family of low molecular weight compounds and have a polyphenolic structure. This comprehensive book explores the therapeutic potential of novel flavonoid derivatives in combating diabetic cataractogenesis. Utilizing a multi-disciplinary approach, the research integrates in silico molecular docking to identify high-affinity aldose reductase inhibitors (ARIs) with traditional chemical synthesis and characterization techniques. The core of the investigation lies in a rigorous in vitro evaluation using isolated goat lenses, demonstrating how these specialized compounds retard lens opacification and mitigate oxidative stress. This book provides a critical scaffold for the development of non-surgical, plant-derived pharmacological interventions for vision preservation.

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Über die Autorin bzw. den Autor

Dr. Vijayabaskaran Manickam is a distinguished academician and researcher with over 27 years of experience in Pharmaceutical Sciences, currently serving as Professor and Head at J.K.K. Nattraja College of Pharmacy, India. Dr. Vijayabaskaran has authored over 90 research publications in reputed national and international journals.

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Verlag
LAP LAMBERT Academic Publishing
Erscheinungsdatum
2026
Sprache
Englisch
ISBN 10 
6209863264
ISBN 13 
9786209863264
Einband
Taschenbuch
Anzahl der Seiten
96
Kontakt zum Hersteller
Fastbook Publishing
customerservice@vdm-vsg.de

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