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Comprehensive Guide to Liver Disorders: Pathophysiology of Liver Disorders: From Cellular Architecture to Disease Evolution - Softcover

El-Banna, Mona; Hassan, Heba

 
9786209926686: Comprehensive Guide to Liver Disorders: Pathophysiology of Liver Disorders: From Cellular Architecture to Disease Evolution

Inhaltsangabe

The liver is a central metabolic organ with a highly specialized structure that supports its diverse physiological functions. This book begins by outlining liver anatomy, including lobular organization, cellular composition, and histological features that regulate metabolism, detoxification, and immune responses. Special emphasis is placed on the hepatic microenvironment-hepatocytes, Kupffer cells, stellate cells, and sinusoidal endothelial cells-and their coordinated roles in maintaining homeostasis.The book then examines key mechanisms of liver injury, focusing on oxidative stress, inflammation, and viral infection as common pathogenic pathways. These processes link major etiological factors, including hepatotropic viruses, alcohol consumption, and metabolic disorders such as non-alcoholic fatty liver disease (NAFLD).Finally, it provides an integrated overview of major liver diseases, including viral hepatitis, alcoholic liver disease, NAFLD, and hepatocellular carcinoma. Emphasis is placed on disease progression from early injury to fibrosis, cirrhosis, and ultimately malignant transformation, highlighting the interconnected nature of chronic liver disorders.

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Über die Autorin bzw. den Autor

Mona Anwar Mohamed El-Bana, a professor at the National Research Centre, advances medical biochemistry through research and teaching. Her work focuses on disease mechanisms, metabolic disorders, and neurodegeneration. She mentors students, contributes to scientific knowledge, and bridges research with clinical applications for improved healthcare.

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