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The Periodontitis-Cancer Axis: Mechanisms, Evidence and Clinical Implications - Softcover

Mahajan, Aashna; Bhat, Geetha K.; Sinha, Soumik

 
9786630211351: The Periodontitis-Cancer Axis: Mechanisms, Evidence and Clinical Implications

Inhaltsangabe

For decades, periodontitis was viewed as a localized inflammatory condition causing tooth loss. Today, it is recognized as a profound systemic disruptor and a critical modifier in the global oncological landscape. The Periodontitis-Cancer Axis provides a comprehensive exploration of how chronic periodontal disease serves as a potent systemic driver for oncogenesis. This book meticulously unravels the complex interkingdom dysbiosis of the oral microbiome, detailing how keystone pathobionts like Porphyromonas gingivalis and Fusobacterium nucleatum translocate to distal organs. By examining the mechanisms of systemic inflammatory overflow, immune subversion, and epigenetic priming, this dissertation connects oral pathogenesis to aerodigestive, gastrointestinal, and hormone-sensitive malignancies, including oral, colorectal, pancreatic, and breast cancers. Bridging the critical gap between clinical periodontology and oncology, this text highlights the undeniable necessity of integrating periodontal management, advanced diagnostics, and targeted therapeutics into comprehensive cancer prevention protocols.

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Über die Autorin bzw. den Autor

I am Dr. Aashna Mahajan, a 27 year-old postgraduate student in Periodontology. Dedicated to excellence in periodontal therapy, implant dentistry, and clinical research, I am passionate about advancing evidence-based practice. My goal is to contribute to periodontal science while improving patient outcomes through academic and clinical excellence.

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