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SYNTHESIS & STUDY OF BIOLOGICALLY ACTIVE COMPOUNDS BY CAT. REACTIONS: SYNTHESIS & STUDY OF BIOLOGICALLY ACTIVE COMPOUNDS - Softcover

Mane, Dhananjay; Pawar, Jyotiba

 
9786630225617: SYNTHESIS & STUDY OF BIOLOGICALLY ACTIVE COMPOUNDS BY CAT. REACTIONS: SYNTHESIS & STUDY OF BIOLOGICALLY ACTIVE COMPOUNDS

Inhaltsangabe

Catalytic reactions encompass a broad range of methodologies, including metal-catalyzed transformations, organocatalysis, and biocatalysis. Transition metal catalysts, such as palladium, copper, and rhodium, have been widely employed in cross-coupling reactions like the Suzuki-Miyaura and Heck reactions, facilitating the construction of complex carbon frameworks found in pharmaceuticals. Organocatalysis, utilizing small organic molecules as catalysts, has emerged as a sustainable alternative, often operating under mild conditions and avoiding the use of heavy metals.The design and synthesis of 4-hydrazinyl-7H-pyrrolo[2,3-d]pyrimidine derivatives and 5-amino-1,3-diphenyl-1H-pyrazole-4-carbonitrile derivatives aim to leverage their heterocyclic scaffolds for potential biological activity, such as antimicrobial, anticancer, or enzyme inhibitory effects. These compounds are structurally tailored to incorporate reactive functional groups-hydrazinyl and amino/nitrile, respectively-that enable further derivatization and enhance interactions with biological targets.

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Über die Autorin bzw. den Autor

Prof. Mane is working as professor in chemistry since three decades. He has guided to many students for their carrear. He gided more than 23 students for Ph. D. Degree and published more than 135 research papers in reputed journal at national and international level.

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