Advancing Methods for Biomolecular Crystallography (NATO Science for Peace and Security Series A: Chemistry and Biology) - Hardcover

Buch 14 von 28: NATO Science for Peace and Security Series A: Chemistry and Biology
 
9789400762312: Advancing Methods for Biomolecular Crystallography (NATO Science for Peace and Security Series A: Chemistry and Biology)
Hardcover
ISBN 10: 9400762313 ISBN 13: 9789400762312
Verlag: Springer, 2013

Inhaltsangabe

This work presents a snapshot of the state of the art of modern biomolecular crystallography, from crystallisation through structure determination and even interactive presentation on the web.  Methods driving the latest automated structure determination pipelines are explained, as well as how to deal with problems such as crystal pathologies that still demand expert analysis.  These methods are illustrated through their application to problems of great biological interest, such as the molecular machinery underlying the complement pathway, the mechanism of action of monoamine oxidase inhibitors, and the structure of the eukaryotic ribosome.  Complementary approaches, such as neutron diffraction, small angle X-ray scattering, coherent diffraction and computational modelling, are also explored.

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This work presents a snapshot of the state of the art of modern biomolecular crystallography, from crystallisation through structure determination and even interactive presentation on the web. Methods driving the latest automated structure determination pipelines are explained, as well as how to deal with problems such as crystal pathologies that still demand expert analysis. These methods are illustrated through their application to problems of great biological interest, such as the molecular machinery underlying the complement pathway, the mechanism of action of monoamine oxidase inhibitors, and the structure of the eukaryotic ribosome. Complementary approaches, such as neutron diffraction, small angle X-ray scattering, coherent diffraction and computational modelling, are also explored.

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Verlag
Springer
Erscheinungsdatum
2013
Sprache
Englisch
ISBN 10 
9400762313
ISBN 13 
9789400762312
Einband
Gebundene Ausgabe
Anzahl der Seiten
375
Herausgeber
Read Randy, Urzhumtsev Alexandre G., Lunin Vladimir Y.
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Weitere beliebte Ausgaben desselben Titels

9789400763197: Advancing Methods for Biomolecular Crystallography (NATO Science for Peace and Security Series A: Chemistry and Biology)

Vorgestellte Ausgabe

ISBN 10:  9400763190 ISBN 13:  9789400763197
Verlag: Springer, 2013
Softcover